Table 1.
Baseline demographics and clinical characteristics of the ITT population.
| Placebo (n = 109) |
L. acidophilus DDS-1 (n = 111) |
B. lactis UABla-12 (n = 110) |
p Value | |
|---|---|---|---|---|
| Mean (SD) or n (%) | Mean (SD) or n (%) | Mean (SD) or n (%) | ||
| Age (years) | 37.61 (10.12) | 39.41 (11.80) | 41.60 (11.11) | 0.028 ‡ |
| Female gender, n (%) | 54 (49.5) | 58 (52.3) | 51 (46.6) | 0.681 † |
| BMI (kg/m2) | 24.10 (4.06) | 24.09 (4.34) | 23.78 (3.98) | 0.811 ‡ |
| Systolic BP (kPa) | 15.89 (1.13) | 15.96 (1.08) | 16.03 (1.11) | 0.660 § |
| Diastolic BP (kPa) | 10.09 (0.94) | 10.33 (0.86) | 10.25 (1.00) | 0.116 § |
| Pulse Rate (bpm) | 78.23 (8.63) | 76.96 (7.69) | 78.18 (8.10) | 0.426 ‡ |
| IBS duration (months) | 20.81 (10.92) | 20.85 (12.29) | 22.07 (12.80) | 0.674 ‡ |
| GAD score | 3.88 (1.81) | 4.04 (1.62) | 4.16 (1.64) | 0.378 § |
| PHQ-9 score | 5.38 (3.15) | 5.61 (3.05) | 5.32 (2.96) | 0.749 ‡ |
| Alcohol consumption | ||||
| None, n (%) | 96 (88.1%) | 100 (90.1%) | 97 (88.2%) | |
| Occasional, n (%) | 3 (2.8%) | 2 (1.8%) | 3 (2.7%) | 0.983 † |
| Not available, n (%) | 10 (9.2%) | 9 (8.1%) | 10 (9.1%) |
† Between group comparison, Pearson Chi Square test; ‡ Between group comparison, one-way ANOVA; § Between group comparison, Kruskal–Wallis test; BMI: body mass index; BP: blood pressure; IBS: irritable bowel syndrome; GAD: generalized anxiety disorder; PHQ: participant health questionnaire; SD: standard deviation.