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Effects of 5-CQA on neuron loss in APP/PS2 mice hippocampus. (A) Nissl-staining neurons in hippocampal CA1, CA2, and CA3 regions of WT, APP/PS2, and APP/PS2 + 5-CQA mice. Scale bar: 50 µm at ×40 magnification. (B) Quantification of Nissl-staining neurons. Data are means ± SEM (n = 5 mice/treatment). *: p < 0.05, ***: p < 0.001 vs. APP/PS2, #: p < 0.05 vs. WT (Bonferroni’s post-hoc test).
