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. 2020 Jan 30;12(2):369. doi: 10.3390/nu12020369

Figure 1.

Figure 1

Effects of Cornus officinalis (CO) and Ribes fasciculatum (RF) extract on mRNA expression of adipogenesis-related genes and the lipid accumulation in 3T3-L1 cells. The cocktail of dexamethasone, 3-isobutyl-1-methylxanthine, and insulin (DMI)-induced 3T3-L1 cells were treated with combined CO and RF of different ratios (6:4, 7:3, or 8:2) and single extracts of CO or RF, and the mRNA expression level of adipogenesis-inducing genes, including Plin1 (A) and Adipoq (B), was calculated quantitatively by qRT-PCR. (C) Lipid accumulation was assessed by oil red O staining and visualized under a microscope. *: p < 0.05 vs. control, #: p < 0.05 vs. 7:3 (50).