Table 2.
Determinants of changes in HOMA-IR in participants during weight loss.
| Model | Parameter | Females | Males | ||
|---|---|---|---|---|---|
| Std ß, Confidence Interval | p-Value | Std ß, Confidence Interval | p-Value | ||
| 1 | Δ-Acetate Mean acetate | 0.111 (0.013 to 0.209) | 0.027 | −0.098 (−0.224 to 0.027) | 0.123 |
| 2 | Model 1 + Age | 0.125 (0.027 to 0.223) | 0.013 | −0.101 (−0.227 to 0.025) | 0.115 |
| 3 | Model 2 + Δ-Weight | 0.120 (0.022 to 0.218) | 0.017 | −0.069 (−0.189 to 0.051) | 0.259 |
| 4 | Model 3 + Δ-Fat-free mass | 0.130 (0.010 to 0.249) | 0.033 | −0.072 (−0.211 to 0.068) | 0.310 |
Linear mixed model was adjusted for age, weight, and fat-free mass. All models were adjusted for center as a random factor (coefficients not shown). Acetate concentration (independent factor) and HOMA-IR as dependent factors. Statistically significant p-values are in bold. Valid cases n = 302 females, 175 males.