Figure 4.

Low intensity vibration training for three or seven days (in Studies 2 and 3, respectively) did not affect muscle mRNA expression of genes associated with inflammation or myogenesis. RNA was isolated from A: gastrocnemius muscles of mdx mice three days following interventions of vibration, wheel running, or eccentric contractions and compared to those of control mdx mice (indicated by the solid gray line) and B: tibialis anterior muscle from mdx, het and dko mice that were vibrated for seven days and compared to genotype-matched, non-vibrated controls (indicated by the solid gray line). The height of the bars indicate the fold change in mRNA expression (i.e., delta-delta CT) above controls and the error bars indicate the 95% confidence intervals. ^aSignificantly different from respective, non-vibrated mdx mice as determined by REST, 2009 software (P<0.05).