Figure 4.
Effect of high-fat diet (HFD) and AICAR treatment in pregnancy (AICAR/P) or lactation (AICAR/L) on mRNA expression of (A) silent information regulator transcript 1 (SIRT1) and 4 (SIRT4); (B) peroxisome proliferator-activated receptor (PPAR) α-, β-, and γ-isoforms; and (C) PPARγ coactivator-1α (PGC-1α) in 16-week-old male offspring kidneys. * p < 0.05 vs. control, # p < 0.05 vs. HFD, † p < 0.05 vs. AICAR/P, ‡ p < 0.05 vs. HFD + AICAR/L.