Figure 6.

Effects of K2 and K6 on mRNA and protein expression of lipogenesis-related genes in the rat model of HF/HF-induced NAFLD. mRNA expression level of (a) SREBP-1c, (b) FAS, and (c) C/EBP in the liver. Western blot analysis of (d) SREBP-1c, (e) FAS, and (f) C/EBP expression in the liver. NC, normal diet control; HC, HF/HF diet control; PC, HF/HF diet with silymarin; K2, HF/HF diet with ATG-K2; K6, HF/HF diet with ATG-K6; SREBP-1c, sterol regulatory element binding protein 1c; FAS, fatty acid synthase; C/EBP, CCAAT/enhancer-binding protein. The data are presented as mean ± SD. Means with different letters (a, b) are significantly different, p < 0.05, whereas those with similar letters are not different. The groups were compared using one-way ANOVA followed by Duncan’s multiple range tests.