Table 1.

Summary of dietary bisphenol S (BPS) exposure and reproduction.

Specific Effect	Model Used	Results	Reference Number
Reproductive System	Zebrafish	Mixed results with 3 studies claiming BPS was the least toxic to developing zebrafish and one study claiming BPS was the most toxic	Moreman et al. [12] Catron et al. [13] Qiu et al. [14] Kinch et al. [15]
	Murine	BPS and BPA decreased sperm counts, sperm quality, and spermatogenesis but only BPS decreased sperm motility. In females, BPS decreased lactation, disrupted follicular development, caused an abnormal estrogen response, increased female infertility and altered maternal behavior	Roelofs et al. [16] Liang et al. [17] Shi et al. [25] LaPlante et al. [18] Catanese & Vandenberg [19] Hill et al. [20] Castro et al. [21] Ohtani et al. [22] Demacopulo & Kreimann [23] Shi et al. [24]
	Bovine	BPS caused the most abnormal oocyte spindle formation & chromosomal misalignment	Campen et al. [26]
	Porcine	BPS inhibited cell proliferation & nonenzymatic scavenging activity causing reproductive toxicity	Berni et al. [27]
	human cell lines or explants	BPS more easily decreased spermatogenesis, BPA and BPS both inhibit early placentation	Eladek et al. [28] Desdoits-Lethimonier et al. [29] Basak & Duttaroy [30]
	Clinical/Observational Studies	BPS was not correlated with lower birth weight and smaller head circumference, but was correlated with lower Corticotropin-releasing hormone (CRH) levels	Mustieles et al. [31] Aker et al. [32]