Table 4.
Number of patients who suffer from late side effects of the KD at every evaluation period.
| Time on the Diet | 3 Months | 6 Months | 12 Months | 2 Years | 3 Years | 4 Years | 5 Years | 6 Years |
|---|---|---|---|---|---|---|---|---|
| Total of patients suffering side effects | 15/26 | 13/26 | 21/26 | 22/26 | 11/18 | 7/12 | 3/8 | 3/6 |
| Constipation | 4 | 3 | 3 | 2 | 1 | - | 2 | 1 |
| Abdominal Pain | - | - | - | 1 | - | - | - | - |
| Nausea/vomiting | 1 | 1 | 1 | 1 | - | 1 | - | - |
| Diarrhea | - | - | - | 1 | - | - | - | - |
| Hypoglycemia | - | - | - | - | - | 1 | - | - |
| Hypercholesterolemia | 6 | 5 | 10 | 8 | 6 | 4 | 1 | 1 |
| Hypertriglyceridemia | 3 | 1 | 2 | 2 | 2 | - | - | 1 |
| Elevated AST, ALT or GGT | 3 | 2 | 1 | 2 | 1 | - | - | - |
| Hypercalciuria | 6 | 6 | 9 | 11 | 4 | 3 | - | 1 |
| Protein in urine | 1 | 4 | 3 | 3 | 1 | 1 | 1 | - |
| Fatigue | 1 | - | - | - | - | - | - | - |
| Anorexia | 1 | - | - | - | - | - | - | - |
| Hyperuricemia | 1 | - | 2 | 4 | 3 | 2 | 1 | 1 |
| Metabolic acidosis (pH) | 2 | - | 4 | 4 | 2 | - | - | - |
AST: aspartate aminotransferase, ALT: alanine aminotransferase, GGT: gamma glutamyl transpeptidase.