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. 2020 Mar 14;6:5. doi: 10.1186/s40738-020-00074-3

Table 3.

Classification of the phases of oestrous cycle based on the cell types and relative number of these cells in vaginal smears (Cora et al., [8])

Oestrous phase Neutrophils Small nucleated epithelial cells Large nucleated epithelial cells Anucleated keratinized epithelial cells Relative cell density
Proestrus 0 to + ++ to +++ 0 to + 0 to + Low to moderate
Estrus
 Rat 0 to + 0 to ++ 0 to ++ ++ to +++ Moderate to high
 Mouse 0 to + 0 to + 0 to + ++ to +++ Moderate to high
Metestrus
 Rat + to +++ + to ++ + to ++ + to +++ Moderate to high
 Mouse + to +++ 0 to + 0 to + ++ to +++ Moderate to high
Diestrus ++ to +++ + to ++ + to ++ 0 to + Low to moderate

0 = none; + = few; ++ = moderate; +++ = high