Table 2.
LncRNAs in tumor VM formation
| LncRNA | Cancer type | Cancer cell lines | miRNA | Signaling pathway | Effect of VM formation |
Reference |
|---|---|---|---|---|---|---|
| MALAT1 | Gastric cancer |
BGC823 SGC7901 |
miR-376a | ERK/MMP FAK/paxillin pathway | Promote | [16, 71] |
| MALAT1 | Lung cancer |
H1299 H292 |
miR-145-5p | lncRNA-MALAT1/miR-145-5p/NEDD9 pathway | Promote | [70] |
| LINC00339 | Glioma |
U87 U251 |
miR-539-5P | miR-539-5P/Twist1/MMPs pathway | Promote | [89] |
| LncRNA n339260 | Hepatocellular carcinoma | HepG2 | - | TGF-β pathway | Promote | [68] |
| LncRNA HOXA-AS2 | Glioma |
U87 U251 |
miR-373 | miR-373/EGFR pathway | Promote | [90] |
| LncRNA TP73-AS1 | Triple negative breast cancer | MDA-MB-231 | miR-490-3P | miR-490-3p/Twist1 pathway | Promote | [94] |
| LINC00312 | Lung adenocarcino-ma |
H1299 PC-9 |
- | YBX1/AKT/TGF-β pathway | Promote | [26] |
| SNHG20 | Glioma |
U87 U251 |
- | ZRANB2/SNHG20/FOXK1 pathway | Promote | [73] |