Table 5.

Negative binomial regression analysis: predictors of falls

Factors	Univariate		Multivariate
			Model 1		Model 2
	RR (95% CI)	P-value	RR (95% CI)	P-value	RR (95% CI)	P-value
Frailty & physical function
Frailty (yes/no)	4.10 (1.60–10.51)	0.003	2.23 (0.85–5.87)	0.103	1.78 (0.70–4.51)	0.224
Daily steps (n°)	0.99 (0.99–1.00)	0.006	1.00 (0.99–1.00)	0.137	1.00 (0.99–1.00)	0.106
Daily sit to stands (n°)	0.96 (0.93–0.99)	0.042	0.98 (0.94–1.02)	0.387	0.99 (0.95–1.04)	0.707
Handgrip (kg)	0.94 (0.88–0.99)	0.034	0.97 (0.92–1.02)	0.216	0.98 (0.93–1.04)	0.448
Gait speed (m/s)	0.08 (0.01–0.62)	0.016	0.26 (0.03–2.08)	0.205	0.36 (0.04–3.32)	0.363
TUG (s)	1.16 (1.02–1.32)	0.021	1.08 (0.96–1.21)	0.220	1.03 (0.91–1.17)	0.643
Cardiovascular function
Total-BEI (%)	0.96 (0.93–0.98)	<0.001	0.96 (0.94–0.99)	0.003	0.96 (0.94–0.99)	0.004
CO (L/min)	0.51 (0.27–0.98)	0.043	0.66 (0.37–1.15)	0.143	0.67 (0.39–1.13)	0.134
OscDBP (mmHg)	0.90 (0.83–0.98)	0.010	0.93 (0.87–0.99)	0.036	0.93 (0.87–0.99)	0.033

Abbreviations: RR rate ratio, CI confidence interval, TUG timed up and go test, Total-BEI total-events baroreceptor effectiveness index, CO cardiac output response to HUT-60°, OscDBP oscillometric diastolic blood pressure response to HUT-60°, Model 1: All factors are adjusted for CRP and antidepressant use, Model 2 Frailty and physical function factors are adjusted for all variables in Model 1 and for Total-BEI. Cardiovascular function factors are adjusted for all variables in Model 1 and for frailty