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. 2020 Mar 14;21:99. doi: 10.1186/s12882-020-01759-z

Table 6.

Further analyses: goodness of fit of negative binomial regression models

Factors Univariate Multivariatea
RR (95% CI) P-value AIC RR (95% CI) P-value AIC ΔAIC
Frailty and physical function
 Frailty (yes/no) 4.10 (1.60–10.5) 0.003 185 2.53 (0.96–6.70) 0.060 149.6 −19.1%
 Daily steps (n°) 0.99 (0.99–1.00) 0.006 142.3 1.00 (0.99–1.00) 0.036 113.2 −20.4%
 Daily sit to stands (n°) 0.96 (0.93–0.99) 0.042 146.7 0.99 (0.95–1.03) 0.543 116.7 − 20.4%
 Handgrip (kg) 0.94 (0.88–0.99) 0.034 188.6 0.97 (0.91–1.03) 0.330 151.8 −19.5%
 Gait speed (m/s) 0.08 (0.01–0.62) 0.016 176.3 0.14 (0.02–1.39) 0.094 141.1 −20.0%
 TUG (s) 1.16 (1.02–1.32) 0.021 171.7 1.10 (0.95–1.27) 0.226 138.5 −19.3%
Cardiovascular function
 Total-BEI (%) 0.96 (0.93–0.98) <0.001 150.8 0.96 (0.94–0.99) 0.003 149.6 −0.8%
 CO (L/min) 0.51 (0.27–0.98) 0.043 168.6 0.58 (0.33–1.04) 0.068 165.7 −1.7%
 OscDBP (mmHg) 0.90 (0.83–0.98) 0.010 144.1 0.92 (0.85–0.99) 0.028 142.6 −1.0%

Abbreviations: RR rate ratio, CI confidence interval, AIC Akaike’s information criterion, TUG timed up and go test, Total-BEI total-events baroreceptor effectiveness index, CO cardiac output, OscDBP oscillometric diastolic blood pressure

aFrailty and physical function variables are adjusted by Total-BEI, cardiovascular function variables are adjusted by frailty