Table 4.

Top 10 abundant COGs of the gut microbiota in native Tibetans.

#COG	Sum (%)	Description
COG1373	1,412,968 (20.35)	ATPase (AAA+superfamily)
NOG00099	850,664 (12.25)	TonB-dependent receptor plug
NOG02827	780,632 (11.24)	ATPase (AAA)
COG0642	739,750 (10.65)	Histidine kinase
COG3250	654,486 (9.43)	Hydrolase family 2
COG0463	568,870 (8.19)	Glycosyltransferase, family 2
COG1472	533,440 (7.68)	Hydrolase family 3
COG0793	474,230 (6.83)	Protease
COG0534	473,946 (6.83)	Mate efflux family protein
COG0745	454,886 (6.55)	DNA-binding response regulator, OmpR family

COG: clusters of orthologous group.