Table 2. Reporting Odds-Ratios (ROR) and 95% confidence intervals of 30 antidepressant compounds based on antidepressant classification included in the study.

Antidepressant classification	Somnolence cases	Other reported cases	Somnolence ROR (95% CI)
Norepinephrine reuptake inhibitor (n = 1)	1,079	17,353	6.6 (6.2–7.1)
Atypical antipsychotic/Selective serotonin reuptake inhibitor (n = 1)	95	2,647	3.8 (3.1–4.7)
Non-competitive N-methyl-D-aspartate receptor antagonist (n = 1)	12	337	3.8 (2.1–6.7)
Tetracyclic antidepressants (n = 4)	894	25,632	3.7 (3.5–4.0)
Monoamine oxidase inhibitors (n = 3)	110	3,254	3.6 (3.0–4.3)
Serotonin-norepinephrine reuptake inhibitors (n = 5)	3,804	134,426	3.1 (3.0–3.2)
Selective serotonin reuptake inhibitors (n = 6)	6,751	250,036	3.1 (3.0–3.1)
Tricyclic antidepressants (n = 5)	1,174	41,009	3.1 (2.9–3.2)
Serotonin antagonist and reuptake inhibitor (n = 1)	721	27,640	2.8 (2.6–3.0)
Norepinephrine-dopamine reuptake inhibitor (n = 1)	1,048	49,599	2.2 (2.1–2.4)
Serotonin modulator and stimulators (n = 2)	122	6,549	2.0 (1.6–2.4)