Take home figure.

The joint association of genetic risk and sleep pattern with cardiovascular disease. Healthy sleep score to each participant was calculated by summing the binary score for each of the low-risk sleep factors: early chronotype; sleep 7–8 h per day; never or rarely insomnia; no snoring; no frequent excessive daytime sleepiness. The overall sleep pattern was defined as healthy (≥4), intermediate (2–3), and poor (≤1) based on the healthy sleep score. The overall genetic risk for each outcome was defined as high (Q5), intermediate (Q2–Q4), and low (Q1) based on the genetic risk score, separately.