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. 2020 Mar 10;12:1801–1808. doi: 10.2147/CMAR.S232734

Table 2.

Differences in the Concentration of Various Tumor Biomarkers Between Elderly Lung Cancer Patients with and Without OM

Tumor Biomarkers OM Group NOM Group t-test P value
ALP (U/L) 108.25±10.39 94.73±1.89 1.281 0.209
Calcium (mmol/L) 2.19±0.03 2.25±0.01 −1.787 0.083
AFP (ng/mL) 3.22±0.39 1.75±0.04 5.559 <0.001
CEA (ng/mL) 416.67±118.08 38.66±4.62 10.377 <0.001
CA-125 (U/mL) 378.63±78.31 64.39±4.22 9.930 <0.001
CA-199 (U/mL) 160.42±53.37 38.95±6.65 2.563 0.010
CA-153 (U/mL) 54.99±10.63 19.32±0.75 6.483 <0.001
CA-724 (U/mL) 9.05±3.88 12.80±3.47 −0.721 0.484
CYFRA21-1(ng/mL) 29.28±4.16 9.37±0.75 4.714 <0.001
TPSA (ng/L) 4.59±0.45 1.63±0.10 6.420 <0.001
NSE (μg/L) 25.77±2.82 25.25±0.97 0.176 0.861
HB (g/L) 108.34±3.55 117.41±0.47 −2.529 0.017

Notes: Independent sample t-test. P < 0.05 denoted statistical significance.

Abbreviations: ALP, Alkaline phosphatase; OM, ocular metastasis; NOM, non-ocular metastasis; HB, hemoglobin.