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. 2020 Mar 9;13:503–516. doi: 10.2147/JPR.S219684

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© 2020 Evans et al.

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IL-1β release (Mean ± SEM) following LPS (TLR4) stimulation (12.5 pg·mL to 10 µg·mL) of PBMC’s obtained from controls: no OC (red circle, solid line), controls: OC (blue square, solid line), dysmenorrhea: no OC (red triangle, dotted line), dysmenorrhea: OC (blue upside down triangle, dotted line), pelvic pain: no OC (red diamond, dashed line), and pelvic pain: OC (blue cross, dashed line). A four-parameter logistic dose-response curve has been fitted to each graph; data obtained from day 1–2 and day 7–10 of each individuals’ menstrual cycle.