Table 1.
Participant (SCOPE ID) | Sex | Age | Viral load (copies/mL) | CD4+ T-cell count (cells per μL) | Time of infection before initiation of therapy (months) | ART duration (years) | Therapeutic regimen | Cell Subsets Available |
---|---|---|---|---|---|---|---|---|
2302 | male | 27 | <40 | 696 | <6 | 4.6 | FPV,RTV, TDF/FTC | Naïve, CM, TM, EM |
2115 | male | 51 | <40 | 601 | <6 | 17.3 | FTC/TDF,NVP | HLA-DR+, HLA-DR-, CM, TM, EM |
2275 | male | 47 | <40 | 1842 | <6 | 15.3 | FTC/TDF,NVP | HLA-DR+, HLA-DR-, CM, TM, EM |
2452 | male | 66 | <40 | 604 | >12 | 3.2 | MVC,RTG,ETR | Naïve, CM, TM, EM |
2026 | male | 59 | <40 | 476 | >12 | 17.7 | TDF,ABC/3TC,RTV,DRV | HLA-DR+, HLA-DR-, Naïve, CM, TM, EM |
2046 | male | 50 | <40 | 1099 | >12 | 16.3 | ECV, EFV/TDF/FTC | HLA-DR+, HLA-DR-, Naïve, CM, TM, EM |
Viral Load, CD4+ T-cell count and ART duration are all as at the time of sampling. FPV, fosamprenavir; RTV, ritonavir; TDF, tenofovir disoproxil fumarate; FTC, emtricitabine; NVP, nevirapine; MVC, maraviroc; RTG, raltegravir; ETR, Etravirine; ABC, abacavir; 3TC, lamivudine; DRV, darunavir; EFV, efavirenz; ECV, entecavir; CM, Central Memory; TM; Transitional Memory; EM, Effector Memory