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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Biol Psychiatry. 2019 Sep 25;87(7):609–618. doi: 10.1016/j.biopsych.2019.09.011

Figure 3.

Figure 3.

Gene-Phenotype network. Shared and specific genetic contributions at different stages or symptoms associated with alcohol use disorders, including alcohol use, indices of alcohol misuse severity (MaxDrinks, AUDIT-P), alcohol dependence, response to alcohol. Only SNPs in genes showing a significant (P < 10–8) association with multiple AUD and alcoholrelated traits, and available from the GWAS catalog at the time of this writing, are included. AUDIT, Alcohol Use Disorder Identification Test; AUDIT-C, Alcohol Use Disorder Identification Test items 1–3; AD, alcohol dependence; AUD, alcohol use disorder; UKB, UK Biobank; MVP, Million Veterans Program; AlcGen, Alcohol Genome-wide Association Consortium; GSCAN, GWAS & Sequencing Consortium of Alcohol and Nicotine use Consortium; GxE, gene by environment interaction; GWAS, genome-wide association study.