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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Pediatr Neurol. 2019 Dec 9;105:41–47. doi: 10.1016/j.pediatrneurol.2019.11.019

Table 2.

Summary of hemorrhage characteristics, treatment, hospital course, outcomes, and univariable association with poor 2-year outcome (N=26)

Hemorrhage Characteristics N (%) OR 95% CI p-value
Hemorrhage pattern
 Isolated IVH (1 IVH+SAH) 8 (31)
 Isolated ICH 6 (23)
 ICH + another compartment (IVH or SAH) 12 (46)
Supratentorial 25 (96)
Hemorrhage volume (n=14)
 <2% TBV 11 (69)
 2–4% TBV 1 (6.3)
 ≥4% TBV 4 (25) 1.1 0.8 – 1.6 0.7
Complicating findings
 Edema 12 (46) 0.5 0.05 – 3.8 0.7
 Hydrocephalus 9 (35) 3.9 0.4 – 56 0.3
 Herniation syndrome 3 (11)
Etiology
 Cavernoma 1 (3.9)
 Coagulopathy 9 (35) 2.0 0.3 – 15 0.5
 Choroid plexus/germinal matrix bleed 6 (23) 0.3 0.04 – 2.1 0.2
 Idiopathic 10 (42) 1.1 0.2 – 7.3 0.9

Treatment & Hospital Course

Interventions 9.6 0.9 – 105 0.06
 Mannitol/hyperosmolar saline 1 (3.9) NA
 AED 16 (62) 1.0
 Transfusion 9 (35) 8.5 0.7 – 495 0.1
 Hematoma evacuation 2 (7.7)
 Ventriculostomy 1 (3.9)
Seizures during hospitalization 14 (54) 1.2 0.1 – 15 1.0
Hospital LOS 10.5 (7 – 18) 1.0 1.0 – 1.1 0.3
ICU LOS 7 (6 – 13) 1.0 0.9 – 1.2 0.5

Outcomes

PSOM (median and IQR)
 2 month (n=22) 0 (0 – 1)
 2 year (n=16) 0.25 (0 – 1.25)
 4 year (n=7) 1 (0 – 1.5)
Overall mortality 4 (20)
*

p<0.05.

IVH – intraventricular hemorrhage; SAH – subarachnoid hemorrhage; ICH – intracerebral hemorrhage; TBV – total brain volume; AED – Antiepileptic drug; LOS – length of stay; ICU – intensive care unit; PSOM – Pediatric Stroke Outcome Measure