Figure 4 A-D.
BBB scores from animals in our primary study after sham surgery (T9 laminectomy) or spinal cord injury (SCI) alone or in combination with testosterone-enanthate (SCI+TE) or TE plus bodyweight-supported treadmill training (SCI+TE+TM). Values are means ± SD, n=8–11 per group, as described in Table 3. Horizontal dashed line indicates voluntary over-ground weight-supported plantar stepping (i.e., BBB ≥9). †Indicates different than pre-surgery (Pre-Sx). Letters indicate differences vs respectively labeled groups at p<0.05 or *p<0.01 (a = vs SHAM, b = vs SCI, c = vs SCI+TE, d = vs SCI+TE+TM). Individual symbols and lines (B–D) represent individual animal values; SHAM values are not shown because all animals exhibited BBB=21 throughout. Note 0/11 SCI, 2/10 SCI+TE, and 6/8 SCI+TE+TM animals exhibited BBB ≥9 at 8-weeks post-surgery.