Table 5.

Study Measures.

Variable Type	Measure	When Measured
Primary outcome	Average of up to 4 0–10 recall numerical scale ratings of pain intensity	All assessment points
Secondary outcomes	PROMIS Depression SF[68] PROMIS Anxiety SF[68] PROMIS Sleep Disturbance SF[68] PROMIS Pain Interference SF[68] PTSD Checklist-Civilian version[69] Patient’s Global Impression of Change[70]	Assessed at all time points except Global Improvement, assessed at post-treatment only.
Mediators: Biological	Change in bandwidth oscillation power: theta, alpha, beta, and gamma bandwidth	EEG measured at pre- and post-treatment only.
Mediators: Psychological	Chronic Pain Acceptance Questionnaire. [71] Pain Catastrophizing Scale [72] Self-Compassion Scale Mindfulness subscale[73] Working Alliance-Short Form [74] Pain Catastrophizing Scale [72] Five Facet Mindfulness Questionnaire- Short Form[75] Working Alliance-Short Form [74] Behavioral Inhibition/Behavioral Activation Systems BIS/BAS[76] Self-report of between-session skill practice	Mediators assessed at all times except working alliance (measured only during treatment and post treatment) and skill practice (not collected at pre-treatment).
Moderators:	Baseline EEG: Theta, alpha, beta, and gamma power Stanford Clinical Hypnotizability Scale [77–79] Outcome Expectancy and Treatment Motivation: Treatment Efficacy Scale [80–82] Pain Type : LANSS[51] and Pain DETECT[83] Cognitive Function: Rey Auditory Verbal Learning Test©, Symbol Digit Modalities Test©, Weschler Adult Intelligence Scale – 4th Edition (Digit Span subtest)©, Trail Making Test©, Wide Range Achievement Test – 4th Edition© Functional Comorbidity Index (FCI)[84]	Baseline and/or Pre-treatment

Notes: PROMIS = Patient Reported Outcomes Measurement Information System