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. Author manuscript; available in PMC: 2021 Mar 13.
Published in final edited form as: ACS Infect Dis. 2020 Jan 24;6(3):393–405. doi: 10.1021/acsinfecdis.9b00354

Figure 3. Brief exposure to TGR inhibitors and worm survival.

Figure 3.

Inline graphic 100 μM, Inline graphic 50 μM, Inline graphic 20 μM, Inline graphic 10 μM. Ex vivo S. mansoni adult worms were exposed to compounds for 1 hour. The worms were then washed and cultured in media without compounds for 5 days. Survival was scored daily. Compound 6 was also tested but no worm killing was seen at all concentrations tested.