5. Univariate and multivariate Cox regression analyses of effect of CD163 and Kindlin-2 expression on OS of GC patients included in tissue array.

Characteristics	Univariate analysis				Multivariate analysis
	HR	95% CI	P		HR	95% CI	P
OS, overall survival; GC, gastric cancer; HR, hazard ratio; 95% CI, 95% confidence interval.
Age (year)			0.452				−
≤60	1				−	−
>60	1.010	0.984−1.037			−	−
Gender			0.841				−
Female	1				−	−
Male	0.952	0.590−1.538			−	−
T stage			0.009				0.288
T1−T2	1				1
T3−T4	2.562	1.269−5.174			1.505	0.708−3.199
N stage			0.037				0.204
N0	1				1
N+	1.839	1.038−3.257			1.484	0.807−2.727
M stage			<0.001				<0.001
M0	1				1
M+	6.216	2.837−13.620			6.580	2.866−15.108
TNM stage			<0.001				−
I−II	1				−	−
III−IV	2.474	1.499−4.084			−	−
CD163			0.019				0.141
Low	1				1
High	2.020	1.124−3.628			1.594	0.857−2.965
Kindlin-2			<0.001				<0.001
Low	1				1
High	3.559	2.119−5.978			3.301	1.892−5.758