2. Correlation analysis of risk factors for LN metastasis beyond the extent of D2 lymphadenectomy (N=102).
| Characteristics | Univariate analysis | Multivariate analysis | ||||||
| No. | LN metastasis beyond the extent of D2 lymphadenectomy (n) | P | OR | 95% CI | P | |||
| Positive
(n=21) |
Negative
(n=81) |
|||||||
| LN, lymph node; OR, odds ratio; 95% CI, 95% confidence interval; *, Fisher’s exact test; **, continuity correction. | ||||||||
| Sex | 0.896 | |||||||
| Male | 57 | 12 | 45 | |||||
| Female | 45 | 9 | 36 | |||||
| Age (year) | 0.048 | |||||||
| ≤65 | 75 | 19 | 56 | |||||
| >65 | 27 | 2 | 25 | |||||
| Tumor size (cm) | 0.966 | |||||||
| ≤4.0 | 53 | 11 | 42 | |||||
| >4.0 | 49 | 10 | 39 | |||||
| Lauren type | 1.000* | |||||||
| Intestinal | 20 | 4 | 16 | |||||
| Diffuse | 77 | 16 | 61 | |||||
| Mixed | 5 | 1 | 4 | |||||
| pT stage | 0.194* | |||||||
| T2 | 19 | 1 | 18 | |||||
| T3 | 7 | 2 | 5 | |||||
| T4a | 72 | 17 | 55 | |||||
| T4b | 4 | 1 | 3 | |||||
| pN stage | <0.001* | 2.533 | 1.368−4.691 | 0.003 | ||||
| N0 | 37 | 0 | 37 | |||||
| N1 | 25 | 3 | 22 | |||||
| N2 | 16 | 5 | 11 | |||||
| N3a | 17 | 7 | 10 | |||||
| N3b | 7 | 6 | 1 | |||||
| Number of total LNs dissected | 0.593** | |||||||
| <16 | 16 | 2 | 14 | |||||
| ≥16 | 86 | 19 | 67 | |||||
| Proportion of LNs metastasis | <0.001* | |||||||
| 0 | 37 | 0 | 37 | |||||
| <10% | 17 | 4 | 13 | |||||
| 10%−40% | 36 | 11 | 25 | |||||
| >40% | 12 | 6 | 6 | |||||
| Extent of LNs metastasis | <0.001 | 5.965 | 1.335−26.650 | 0.019 | ||||
| Peri-gastric | 66 | 3 | 63 | |||||
| Extra-gastric | 36 | 18 | 18 | |||||