2. PFTs pre-chemotherapy and post-chemotherapy.
| Parameters | Pre-chemotherapy (
)
|
Post-chemotherapy (
)
|
P |
| PFTs, pulmonary function tests; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second; FEV1%, FEV1/FVC; MMEF25−75, maximum mid-expiratory flow; MVV, maximal voluntary ventilation; TLC, total lung capacity; RV, residual volume; VC, vital capacity; VT, tidal volume; DLCO, carbon monoxide diffusing capacity; DLCO%, percentage of the DLCO predicted value. | |||
| Ventilation function | |||
| FVC (L) | 3.03±0.55 | 3.07±0.58 | 0.406 |
| FEV1 (L/s) | 2.41±0.41 | 2.39±0.46 | 0.598 |
| FEV1% | 79.97±7.78 | 77.75±5.98 | 0.061 |
| MMEF25−75(L/s) | 2.30±0.67 | 2.14±0.69 | 0.141 |
| MVV (L/s) | 89.85±19.81 | 97.89±20.15 | 0.004 |
| Lung capacity | |||
| TLC (L) | 4.63±0.85 | 4.54±0.84 | 0.283 |
| RV (L) | 1.66±0.47 | 1.64±0.37 | 0.822 |
| RV/TLC | 35.59±5.31 | 36.15±5.53 | 0.649 |
| VC (L) | 3.09±0.50 | 3.09±0.59 | 0.914 |
| VT (L) | 0.64±0.29 | 0.68±0.21 | 0.341 |
| Diffusion function | |||
| DLCO (mmoL/kPa/min) | 6.93±0.81 | 5.86±1.08 | <0.001 |
| DLCO% | 90.2±11.8 | 78.8±14.2 | <0.001 |