Table 2.
Parameter | Baseline | End of bypass | 90 min after bypass | Interaction P value |
---|---|---|---|---|
HR (bpm) | ||||
Control group | 109 ± 18 | 111 ± 16 | 118 ± 19 | <0.001 |
CPB group | 101 ± 17 | 128 ± 17* | 124 ± 22 | |
LP group | 93 ± 10 | 90 ± 14†‡ | 101 ± 17‡ | |
MAP (mm Hg) | ||||
Control group | 69 ± 6 | 79 ± 9 | 74 ± 7 | 0.11 |
CPB group | 66 ± 9 | 67 ± 14 | 61 ± 5 | |
LP group | 68 ± 6 | 66 ± 17 | 56 ± 6 | |
PAP mean (mm Hg) | ||||
Control group | 18 ± 1 | 19 ± 2 | 19 ± 4 | 0.08 |
CPB group | 17 ± 2 | 17 ± 2 | 17 ± 2 | |
LP group | 19 ± 2 | 22 ± 3 | 21 ± 3 | |
PCWP (mm Hg) | ||||
Control group | 11 ± 2 | 11 ± 1 | 12 ± 2 | 0.37 |
CPB group | 10 ± 3 | 9 ± 4 | 9 ± 3 | |
LP group | 12 ± 2 | 12 ± 2 | 12 ± 1 | |
CI (L·min−1·m−2) | ||||
Control group | 3.9 ± 0.8 | 4.2 ± 0.8 | 4.2 ± 1 | 0.03 |
CPB group | 4 ± 0.6 | 3.6 ± 0.8 | 3.2 ± 0.5† | |
LP group | 3.8 ± 0.9 | 4.1 ± 0.7 | 3.6 ± 0.4 | |
SVRI (dynes·s·cm−5·m−2) | ||||
Control group | 1314 ± 332 | 1415 ± 291 | 1315 ± 248 | 0.02 |
CPB group | 1204 ± 206 | 1348 ± 385 | 1350 ± 208 | |
LP group | 1290 ± 292 | 1070 ± 294 | 1038 ±162‡ | |
PVRI (dynes·s·cm−5·m−2) | ||||
Control group | 144 ± 52 | 154 ± 66 | 150 ± 72 | 0.36 |
CPB group | 152 ± 83 | 187 ± 61 | 210 ± 72 | |
LP group | 155 ± 44 | 191 ± 38 | 209 ± 61 | |
RVSWI (g·m−2·beat−1) | ||||
Control group | 5 ± 1 | 6 ± 1 | 6 ± 2 | <0.001 |
CPB group | 6 ± 1 | 4 ± 2 | 4 ± 1 | |
LP group | 5 ± 2 | 8 ± 3*‡ | 6 ± 1 | |
LVSWI (g·m−2·beat−1) | ||||
Control group | 28 ± 6 | 34 ± 7 | 30 ± 5 | <0.001 |
CPB group | 31 ± 9 | 22 ± 4† | 19 ± 4*† | |
LP group | 31 ± 8 | 35 ± 13 | 22 ± 4*† |
bpm = beats per minute; CI = cardiac index; CPB = cardiopulmonary bypass; HR = heart rate; LP = lung perfusion; LVSWI = left ventricular systolic work index; MAP = mean arterial pressure; PAP = pulmonary arterial pressure; PCWP = pulmonary artery occlusion pressure; PVRI = pulmonary vascular resistance; RVSWI = right ventricular systolic work index; SVRI = systemic vascular resistance index.
P < 0.05 compared with baseline.
P < 0.05 compared with control group at the same moment.
P < 0.05 compared with CPB group at the same moment.