Table 1.
Long-term outcome of Ramsay Hunt syndrome facial palsy combined from patient records and patient’s self-assessment questionnaire and compared to initial facial palsy grade
| Medication at Ramsay Hunt syndrome onset | Number of patients (total = 120) | Medication onset time from Ramsay Hunt diagnose/patient number Initial HB gradea –› outcomeb/patient number |
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|---|---|---|---|---|---|
| ≤ 24 h | ≤ 48 h | ≤ 72 h | > 72 h | ||
| Valaciclovir orally 1 g × 3 × 7 | 18 |
15 HB II –› 1/3 HB III –› 1/1 HB VI –› 2/1 HB ? –› 1/3 HB ? –› 2/6 HB ? –› 3/1 |
1 HB ? –› 1/1 |
2 HB II –›1/1 HB ? –› 2/1 |
|
| Valaciclovir orally, dosing unclear | 3 |
3 HB V –›1/1 HB V –› 2/1 HB ? –› 1/1 |
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| Valaciclovir orally 1 g × 3 × 7 + corticosteroidc | 41 |
37 HB II –› 1/1 HB III –› 1/2 HB III –› 4/1 HB IV –› 1/4 HB IV –› 2/2 HB IV –›?/1 HB V –›1/1 HB V –› 2/1 HB V –› 3/1 HB VI –› 1/3 HB VI –› 3/3 HB VI –› ?/1 HB ? –› 1/7 HB ? –› 2/7 HB ? –› 3/2 |
2 HB II –› 1/1 HB V –› 1/1 |
1 HB V –› 1/1 |
1 HB V –› 3/1 |
| Aciclovir orally 800 mg × 5 × 7 | 9 |
7 HB III –› 2/1 HB III –› ?/1 HB IV –› 2/1 HB V –›1/1 HB ? –› 1/3 |
2 HB VI –› 2/1 HB ? –› 1/1 |
||
| Aciclovir orally 800 mg × 5 × 7 + corticosteroidc | 3 |
3 HB II –› 2/1 HB VI –› 3/1 HB ? –› 1/1 |
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| Aciclovir orally, dosing under 800 mg × 5 × 7 or unclear | 9 |
7 HB IV –› 1/1 HB ? –› 1/4 HB ? –›2/2 |
1 HB ? –› 3/1 |
1 HB ? –›?/1 |
|
| Aciclovir intra venous under 10 mg/kg/day × 3 or unclear | 3 |
3 HB II –› 1/1 HB IV –› 1/1 HB ?–› 4/1 |
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| Aciclovir orally under 800 mg × 5 × 7 or intra venous under 10 mg/kg/day × 3 + corticosteroidc | 3 |
3 HB II –› 1/1 HB V –› 2/1 HB ? –›1/1 |
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| Aciclovir intra venous minimum 10 mg/kg/day × 3 | 19 |
14 HB II –›1/1 HB III –›1/1 HB V –› 1/1 HB V –› 2/1 HB V –› 3/1 HB VI –› 2/1 HB VI –› 3/1 HB ? –› 1/3 HB ? –› 2/2 HB ? –› 4/1 HB ? –›?/1 |
2 HB ? –› 1/1 HB ? –› 1/1 |
3 HB II –› 3/1 HB II –›1/1 HB VI –› 4/1 |
|
| Aciclovir intra venous minimum10 mg/kg/day × 3 + corticosteroidc | 10 |
7 HB II –› 2/1 HB IV –› 1/1 HB V –› 1/2 HB V –› 3/1 HB VI –› 4/1 HB ? –› 2/1 |
1 HB V –› 2/1 |
2 HB ? –› 3/1 HB ? –›1/1 |
|
| No medication | 2 |
2 HB ? –› 2/1 HB ? –› 3/1 |
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Patients are grouped by the medication type and medication start time at syndrome onset
aInitial facial palsy grade was available from 62 patient records, graded by House-Brackmann scale (HB) or Sunnybrook scale, latter converted here to HB grades
bFacial palsy outcome: 1—totally recovered; 2—slight sequelae; 3—obvious sequelae; 4—severe sequelae
cCorticosteroid usually Prednisolon 60 mg/day with tapering dosing 10 mg/day after 5 days for 10 days or Medrol 32 mg or 64 mg/day for 7–10 days