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. 2020 Feb 5;9(2):370. doi: 10.3390/cells9020370

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Influence of blood contamination on the quantification of aSyn using ELISA and label-free-based MS using artificially blood-contaminated CSF. Comparative quantification of aSyn in non- and artificially blood-contaminated CSF samples in the range of 0.001% to 0.1% from four different individuals (CSF 1 to CSF 4) was performed with ELISA (A) and MS-based analysis (B). Shown are in (A) the aSyn concentrations in ng/mL and in (B) the relative abundance obtained with the data analysis utilizing the MS software Progenesis QI.