Figure 3.

Patterns of response according to the size and number of the tumors and in function of time of examination. Complete response, partial response, stable disease, and progression are the four classical patterns of response in oncology. Concerning the atypical responses sometimes observed with immune-checkpoint inhibitors, a dissociated response corresponds to lesions shrinking and others growing; pseudoprogression is an initial increase in tumor size and/or number due to inflammation followed by a decrease, and hyperprogression is an accelerated tumor growth rate after starting treating.