Table 2.

List of important small molecule inhibitors and their mechanism of action.

Target	Mechanism	Compound	Reference
Telomerase	Target TERT	BIBR1532	[141,142,143,144,145,146,147]
		TMPI	[148]
		EGCG and MST312	[149,150]
		AZT	[151,152,153]
	Target hTR	Imetelstat	[77,82,154,155,156,157,158,159]
	Peptide vaccine	GRNVAC1, GV1001	[160,161]
Telomere	Target G-quadruplex	Telomestatin	[162,163,164]
		RHPS4	[165,166,167,168]
		BRACO-19
		Quarfloxin	[169,170]
		TMPyP4	[171,172]
CST complex	CTC1, STN1, TEN1	N/A	N/A
Shelterin	Target POT1	SYSU-00692	[77]
	Target TFR2	Gemcitabine	[156,173,174]
	Target TFR1	ETP-47228, ETP-47037	[175]
T-loop	Target t-loop	t-oligos	[176,177,178,179,180]
Post-translational modifications	TRF1-PARsylation	PARP inhibitors	[181,182,183]