Table 3.
Summary of CTC-positive mBC patient samples and their corresponding CTC counts analyzed by either manual or XCyto® 10 -based semi-automated screening. Cases in which one approach yielded higher CTC counts are marked in bold. The evaluation contains CTC-positive samples from prior analysis (Table S3) as well as 6 additional CTC-positive mBC samples (Table S3, Sheet 2). In the cases of “re-evaluated” samples (1) indicates samples processed via the 6.5 μm cassette gap and (2) samples that were separated via the 10 μm gap size. The 6 additional blood samples were solely processed using the narrow 6.5 μm cassette gap. All samples were drawn in EDTA.
| Sample No. (CTC pos.) | Sample ID | CTC Count (Manual Screening) | CTC Count (XCyto10 Screening) |
|---|---|---|---|
| 1 | mBCa_15 (1) | 14 | 13 |
| 2 | mBCa_15 (2) | 6 | 6 |
| 3 | mBCa_22 (1) | 1 | 2 |
| 4 | mBCa_22 (2) | 0 | 1 |
| 5 | mBCa_26 (1) | 5 | 5 |
| 6 | mBCa_27 (1) | 4 | 4 |
| 7 | mBCa_27 (2) | 0 | 1 |
| 8 | mBCA_29 (1) | 14 | 17 |
| 9 | mBC_38 | 2 | 2 |
| 10 | mBC_39 | 1 | 1 |
| 11 | mBC_40 | 42 | 38 |
| 12 | mBC_41 | 1 | 1 |
| 13 | mBC_42 | 7 | 5 |
| 14 | mBC_43 | 1 | 1 |
| Total CTC count detected | 98 | 97 | |