Skip to main content
. 2020 Feb 5;9(2):365. doi: 10.3390/cells9020365

Figure 4.

Figure 4

The effect of clemizole hydrochloride on persistent firing. (A) Example of persistent firing in CCh (10 µM). (B) Suppressed persistent firing in clemizole (CLE, 3 µM) in the same cell shown in (A). (C) Current injection used in (A,B) (100 pA, 2 s). (D) Percentages of cells that showed persistent firing in CCh and during the application of CLE. (E) Post-stimulus firing frequency (Wilcoxon test, * p ≤ 0.05, n = 9). (F) Post-stimulus depolarization (Wilcoxon test, * p ≤ 0.05, n = 9). Clemizole significantly suppressed persistent firing.