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. 2020 Feb 5;9(2):365. doi: 10.3390/cells9020365

Figure 6.

Figure 6

The effect of intracellular application of TRPC4 antibody (1:100) on persistent firing. (A) Example of persistent firing recorded 5 min after the rupturing of the membrane. (B) Suppressed persistent firing recorded 15 min after the rupturing of the membrane in the same cell shown in (A). (C) Current injection used in (A,B) (100 pA, 2 s). (D) Percentages of cells that showed persistent firing in control (5 min) and 15 min after the rupturing of the membrane. (E) Post-stimulus firing frequency (Wilcoxon test, * p ≤ 0.05, n = 7). (F) Post-stimulus depolarization (Wilcoxon test, * p ≤ 0.05, n = 7). TRPC4 antibody significantly suppressed persistent firing.