Table 1.
Panel of breast cancer cell lines with molecular subtype, receptor status and list of mutations [27]. Molecular subtypes are classified as Luminal (green), Basal B (blue) and Basal A (orange).
| Cell Line | Molecular Subtype | Receptor Status | Mutation Summary |
|---|---|---|---|
| AU-565 | Luminal | HER2amp | TP53, MLL3 |
| BT-549 | Basal B | TNBC | TP53, PTEN |
| HCC1428 | Luminal | HR+ | TP53 |
| HCC1569 | Basal A | HER2amp | TP53, MLL3, BRCA2, PTEN |
| HCC1954 | Basal A | HER2amp | TP53, PIK3CA |
| Hs578T | Basal B | TNBC | TP53 |
| MCF-7 | Luminal | HR+ | PIK3CA, GATA3 |
| MDA-MB-157 | Basal B | TNBC | TP53, MAP3K1 |
| MDA-MB-175-VII | Luminal | HR+ | MLL3 |
| MDA-MB-231 | Basal B | TNBC | TP53 |
| MDA-MB-361 | Luminal | HR+ | TP53, PIK3CA, BRCA2 |
| MDA-MB-468 | Basal A | TNBC | TP53, MLL3, PTEN |
| T47D | Luminal | HR+ | TP53, PIK3CA, MLL3 |
| ZR-75-1 | Luminal | HR+ | PTEN |