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Superficially invasive colon carcinoma. (A) H&E staining of a superficially invasive intestinal adenocarcinoma with neoplastic growth limited to the submucosa; (B) CAFs show expression of α-SMA; (C) Pancytokeratin is expressed by cancer cells and absent in fibroblasts; (D) Calretinin-negative myofibroblasts and tumor cells.
