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Norrin enhances N-methyl-D-aspartate (NMDA) induced Lif expression in mice retinae. Real-time RT-PCR on retinal total RNA for Lif from heterozygous (Lif+/−) and homozygous, Lif-deficient mice (Lif−/−), as well as wild-type (WT) littermates 7 h after intravitreal injection of 3 µL PBS, 3 µL NMDA [10 mM] or 3 µL NMDA [10 mM] with Norrin [5 ng/µL]. * p < 0.05; *** p < 0.001.
