Table 2.
Mutation status for TDP1 and TOP1 in parental and olaparib-resistant cells.
| Cell Line | TDP1 | TOP1 |
|---|---|---|
| SNU-484/parental cells | wild type | wild type |
| SNU-484/olaparib-resistant cells | wild type | wild type |
| SNU-601/parental cells | wild type | wild type |
| SNU-601/olaparib-resistant cells | A520D | wild type |
| SNU-668/parental cells | wild type | wild type |
| SNU-668/olaparib-resistant cells | wild type | wild type |
| KATO-III/parental cells | wild type | wild type |
| KATO-III/olaparib-resistant cells | wild type | wild type |
TDP1, tyrosyl-DNA phosphodiesterase 1; TOP1, topoisomerase 1.