Table 3.
Genetic Variant | All Women | Post PV Report | ||||
---|---|---|---|---|---|---|
Years after Initial Breast Cancer | Cumulative Risk (%) | 95% CI | Years after Initial Breast Cancer | Cumulative Risk (%) | 95% CI | |
BRCA1 | 5 | 10.5 | 6.37–17.2 | 5 | 16.6 | 8.0–32.5 |
10 | 32.3 | 24.0–42.6 | 10 | 16.6 | 8.0–32.5 | |
15 | 51.5 | 40.7–63.4 | 15 | 16.6 | 8.0–32.5 | |
20 | 56.6 | 44.8–69.1 | 20 | 16.6 | 8.0–32.5 | |
BRCA2 | 5 | 7.2 | 3.5–14.6 | 5 | 2.0 | 0.3–13.5 |
10 | 20.7 | 13.0–32.1 | 10 | 15.1 | 2.9–60.4 | |
15 | 40.9 | 28.3–56.4 | 15 | 15.1 | 2.9–60.4 | |
20 | 45.3 | 31.4–61.9 | 20 | 15.1 | 2.9–60.4 | |
TP53 | 5 | 19.1 | 8.0–41.8 | 5 | 27.9 | 9.3–66.6 |
10 | 53.1 | 29.6–80.6 | 10 | 56.8 | 20.5–95.3 | |
15 | 64.9 | 38.2–89.7 | 15 | 56.8 | 20.5–95.3 | |
20 | 82.4 | 49.9–98.8 | 20 | 56.8 | 20.5–95.3 |