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. 2020 Feb 7;12(2):378. doi: 10.3390/cancers12020378

Table 3.

Cumulative risk of developing contralateral breast cancer by time after initial breast cancer diagnosis (excludes synchronous).

Genetic Variant All Women Post PV Report
Years after Initial Breast Cancer Cumulative Risk (%) 95% CI Years after Initial Breast Cancer Cumulative Risk (%) 95% CI
BRCA1 5 10.5 6.37–17.2 5 16.6 8.0–32.5
10 32.3 24.0–42.6 10 16.6 8.0–32.5
15 51.5 40.7–63.4 15 16.6 8.0–32.5
20 56.6 44.8–69.1 20 16.6 8.0–32.5
BRCA2 5 7.2 3.5–14.6 5 2.0 0.3–13.5
10 20.7 13.0–32.1 10 15.1 2.9–60.4
15 40.9 28.3–56.4 15 15.1 2.9–60.4
20 45.3 31.4–61.9 20 15.1 2.9–60.4
TP53 5 19.1 8.0–41.8 5 27.9 9.3–66.6
10 53.1 29.6–80.6 10 56.8 20.5–95.3
15 64.9 38.2–89.7 15 56.8 20.5–95.3
20 82.4 49.9–98.8 20 56.8 20.5–95.3