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. 2020 Feb 18;10(2):324. doi: 10.3390/biom10020324

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Altered cell cycle progression and apoptosis of OCI-LY3 cells due to HEDO (10 μM). (A) Percentage of cells in the subG0/G1, G0/G1, S, and G2/M phases after treatment with each compound. Cells were analyzed through flow cytometry. (B) Cell cycle analysis of cells from the same three experiments. *** p < 0.001 versus control group. (C) OCI-LY3 cells were either treated with HEDO or untreated for 72 h and apoptosis was subsequently evaluated through flow cytometry. (D) Quantification of apoptotic cells. Values indicate the means ± SEM. (n = 3, *** p ≤ 0.001).