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Matrilin-2 activates PKR and NF-κB in human AVICs. Human AVICs were stimulated with recombinant matrilin-2 for varied durations. Stimulation with recombinant matrilin-2 resulted in increased levels of phospho-PKR and phospho-NF-κB. Values are means ± SE. n = 5 experiments using distinct cell isolates; * P < 0.05 vs. control.
