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. 2020 Jan 23;12(2):279. doi: 10.3390/cancers12020279
17β-HSD 17β-hydroxysteroid-dehydrogenase
3β-HSD 3β-hydroxysteroid-dehydrogenase
AD 4-androstene-3,17-dione
CYP cytochrome P450
DHEA dehydroepiandrosterone
DHEA-S dehydroepiandrosterone-3-sulfate
DMEM/F-12 Dulbecco’s modified Eagle medium F-12
DPBS Dulbecco’s phosphate buffered saline
E1 estrone
E1-S estrone-3-sulfate
E2 17β-estradiol
E2-G 17β-estradiol-3-O-(β-d-glucuronide)
E2-S 17β-estradiol-3-sulfate
E3 estriol
EOC epithelial ovarian cancer
ERα estrogen receptor alpha
ESR1 estrogen receptor alpha gene
ESR2 estrogen receptor beta gene
ESRRG estrogen-related receptor gamma gene
FBS fetal bovine serum
HGSOC high grade serous ovarian cancer
IL-6 interleukin-6
IL-6R interleukin-6 receptor
Km Michaelis constant
LC-HRMS liquid chromatography high-resolution mass spectrometry
LLOQ lower limit of quantification
PARP poly(ADP-ribose)-polymerase 1
PXR pregnane X receptor
STR short tandem repeats
SULT sulfotransferase
T testosterone
TCZ tocilizumab
UGT uridine 5’-diphospho-glucuronosyltransferase
VEGF vascular endothelial growth factor
Vmax maximum reaction velocity