Figure 1.

Skin localization and cellular morphology of papillary dermis fibroblasts (Fp), reticular dermis fibroblasts (Fr), and dermo-hypodermal junction (DHJ) fibroblasts. (A) Representation of the papillary dermis, reticular dermis, and dermo-hypodermis junction areas. A typical full-thickness skin section is shown, as well as schemes of the three areas of interest. (B) Photographs of skin pieces taken from the below side after fat tissue removal, showing the macroscopic aspect of the conjunctival junctions that connect the dermis to the hypodermis. (C) Cellular morphology of cultured Fp, Fr, and DHJ fibroblasts. In F-DHJ cultures, red arrows point to small tricuspid cells and white arrows to large cells with a visible trabecular cytoplasmic network.