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. 2020 Feb 5;9(2):368. doi: 10.3390/cells9020368

Table 3.

Transcripts related to the tissue skeleton differentially expressed in reticular dermis fibroblasts (Fr) and dermo-hypodermal junction fibroblasts (F-DHJ). This transcript list was extracted from microarray data using a fold-change >1.5 and p < 0.05 as inclusion parameters. The transcript signature with predominant expression in Fr cells concerned 297 probe sets corresponding to transcripts directly involved in the tissue skeleton structure, comprising 33 transcripts related to the extracellular matrix (ECM), 125 focal adhesion point transcripts, 60 cytoskeleton transcripts, 1 LINC complex transcript, and 8 nucleoskeleton transcripts. The transcript signature with predominant expression in F-DHJ cells concerned 359 probe sets corresponding to transcripts directly involved in the tissue skeleton structure, comprising 94 transcripts related to ECM, 76 focal adhesion point transcripts, 50 cytoskeleton transcripts, 1 LINC complex transcript, and 7 nucleoskeleton transcripts. In addition, transcripts encoding soluble factors were found in both signatures, respectively 70 and 131 for Fr and F-DHJ cells.

UP in Fr UP in F-DHJ
Extracellular Matrix Genes
Probe Set ID Gene Symbol Gene Title adj-pval FC Probe Set ID Gene Symbol Gene Title adj-pval FC
205941_s_at COL10A1 collagen, type X, alpha 1 9.41 × 10−3 4.23 220518_at ABI3BP ABI family, member 3 (NESH) binding protein 2.37 × 10−2 2.92
211343_s_at COL13A1 collagen, type XIII, alpha 1 1.44 × 10−2 2.26 1559077_at ABI3BP ABI family, member 3 (NESH) binding protein 7.43 × 10−2 2.49
211809_x_at COL13A1 collagen, type XIII, alpha 1 2.74 × 10−2 1.74 222486_s_at ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 2.76 × 10−2 2.33
221900_at COL8A2 collagen, type VIII, alpha 2 2.88 × 10−1 2.23 222162_s_at ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 4.36 × 10−2 1.91
226824_at CPXM2 carboxypeptidase X (M14 family), member 2 2.01 × 10−1 1.88 226997_at ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 3.75 × 10−3 2.78
221541_at CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 5.98 × 10−2 2.03 214913_at ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.94 × 10−2 1.94
206595_at CST6 cystatin E/M 2.34 × 10−2 3.12 237411_at ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 1.36 × 10−1 1.61
225681_at CTHRC1 collagen triple helix repeat containing 1 1.31 × 10−2 2.82 224396_s_at ASPN asporin 2.47 × 10−2 4.48
202450_s_at CTSK cathepsin K 2.05 × 10−1 1.76 219087_at ASPN asporin 1.32 × 10−2 3.54
213068_at DPT dermatopontin 8.16 × 10−2 3.67 203477_at COL15A1 collagen, type XV, alpha 1 2.18 × 10−1 2.78
207977_s_at DPT dermatopontin 1.24 × 10−1 2.85 209082_s_at COL18A1 collagen, type XVIII, alpha 1 6.56 × 10−4 2.99
222885_at EMCN endomucin 6.59 × 10−2 2.74 209081_s_at COL18A1 collagen, type XVIII, alpha 1 3.92 × 10−3 2.83
227874_at EMCN endomucin 2.70 × 10−1 1.81 208096_s_at COL21A1 collagen, type XXI, alpha 1 1.12 × 10−2 6.88
219436_s_at EMCN endomucin 1.79 × 10−1 1.77 232458_at COL3A1 Collagen, type III, alpha 1 6.64 × 10−3 2.66
224374_s_at EMILIN2 elastin microfibril interfacer 2 6.75 × 10−2 1.68 211981_at COL4A1 collagen, type IV, alpha 1 2.12 × 10−3 1.93
203088_at FBLN5 fibulin 5 2.24 × 10−2 1.88 211980_at COL4A1 collagen, type IV, alpha 1 1.66 × 10−3 1.61
203638_s_at FGFR2 fibroblast growth factor receptor 2 3.21 × 10−3 4.52 222073_at COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 2.28 × 10−2 1.70
208228_s_at FGFR2 fibroblast growth factor receptor 2 2.04 × 10−2 2.52 229779_at COL4A4 collagen, type IV, alpha 4 2.85 × 10−8 5.32
210187_at FKBP1A FK506 binding protein 1A, 12 kDa 8.48 × 10−2 1.81 214602_at COL4A4 collagen, type IV, alpha 4 2.30 × 10−5 4.16
226145_s_at FRAS1 Fraser syndrome 1 6.34 × 10−2 2.31 213110_s_at COL4A5 collagen, type IV, alpha 5 1.05 × 10−1 3.62
204983_s_at GPC4 glypican 4 3.14 × 10−2 2.07 52255_s_at COL5A3 collagen, type V, alpha 3 2.47 × 10−3 3.07
204984_at GPC4 glypican 4 1.57 × 10−2 2.02 218975_at COL5A3 collagen, type V, alpha 3 2.83 × 10−3 2.65
235944_at HMCN1 hemicentin 1 3.52 × 10−5 6.28 205832_at CPA4 carboxypeptidase A4 2.37 × 10−2 4.34
203417_at MFAP2 microfibrillar-associated prot 2 8.08 × 10−2 1.70 201116_s_at CPE carboxypeptidase E 7.11 × 10−3 2.37
204580_at MMP12 matrix metallopeptidase 12 (macrophage elastase) 2.58 × 10−1 2.17 201117_s_at CPE carboxypeptidase E 4.90 × 10−3 2.10
205828_at MMP3 matrix metallopeptidase 3 4.79 × 10−3 7.70 227138_at CRTAP cartilage associated protein 1.31 × 10−2 1.63
209596_at MXRA5 matrix-remodelling associated 5 2.09 × 10−2 2.52 201360_at CST3 cystatin C 6.11 × 10−2 1.55
236088_at NTNG1 netrin G1 2.16 × 10−2 2.55 201487_at CTSC cathepsin C 6.11 × 10−5 2.41
222722_at OGN osteoglycin 1.91 × 10−1 2.04 225646_at CTSC cathepsin C 1.80 × 10−3 2.32
228186_s_at RSPO3 R-spondin 3 homolog (X. laevis) 1.35 × 10−2 2.98 225647_s_at CTSC cathepsin C 1.37 × 10−3 2.25
218638_s_at SPON2 spondin 2, extracellular matrix prot 3.07 × 10−2 2.84 231234_at CTSC cathepsin C 5.72 × 10−3 2.03
216005_at TNC Tenascin C 1.24 × 10−2 2.61 202295_s_at CTSH cathepsin H 4.00 × 10−2 1.85
201645_at TNC tenascin C 4.34 × 10−2 1.59 209335_at DCN decorin 1.02 × 10−1 2.05
211896_s_at DCN decorin 2.16 × 10−1 1.69
211813_x_at DCN decorin 1.52 × 10−1 1.68
201893_x_at DCN decorin 1.77 × 10−1 1.56
1568779_a_at ECM2 extracellular matrix protein 2 1.76 × 10−1 1.71
206101_at ECM2 extracellular matrix protein 2 2.50 × 10−1 1.57
201843_s_at EFEMP1 EGF-containing fibulin-like extracellular matrix protein 1 7.68 × 10−4 3.62
201842_s_at EFEMP1 EGF-containing fibulin-like extracellular matrix protein 1 4.62 × 10−4 2.87
228421_s_at EFEMP1 EGF-containing fibulin-like extracellular matrix protein 1 2.23 × 10−1 1.61
226911_at EGFLAM EGF-like, fibronectin type III and laminin G domains 3.95 × 10−3 4.36
204834_at FGL2 fibrinogen-like 2 4.12 × 10−4 6.37
227265_at FGL2 fibrinogen-like 2 4.28 × 10−3 3.56
202709_at FMOD fibromodulin 1.12 × 10−3 2.96
205206_at KAL1 Kallmann syndrome 1 sequence 9.65 × 10−4 7.84
227048_at LAMA1 laminin, alpha 1 2.82 × 10−1 1.83
216840_s_at LAMA2 laminin, alpha 2 5.17 × 10−3 2.80
205116_at LAMA2 laminin, alpha 2 1.05 × 10−2 2.67
213519_s_at LAMA2 laminin, alpha 2 1.10 × 10−2 2.57
210150_s_at LAMA5 laminin, alpha 5 4.86 × 10−2 1.57
211651_s_at LAMB1 laminin, beta 1 8.27 × 10−2 1.54
200770_s_at LAMC1 laminin, gamma 1 (formerly LAMB2) 7.61 × 10−6 1.91
200771_at LAMC1 laminin, gamma 1 (formerly LAMB2) 7.75 × 10−7 1.90
202267_at LAMC2 laminin, gamma 2 7.41 × 10−4 10.0
200923_at LGALS3BP LOC100133842 lectin, galactoside-binding, soluble, 3 binding protein similar to lectin, galactoside-binding, soluble, 3 binding protein 1.02 × 10−2 2.45
242767_at LMCD1 LIM and cysteine-rich domains 1 1.72 × 10−2 2.01
202998_s_at LOXL2 lysyl oxidase-like 2 4.16 × 10−3 1.59
227145_at LOXL4 lysyl oxidase-like 4 3.15 × 10−2 2.43
219922_s_at LTBP3 latent transforming growth factor beta binding protein 3 7.19 × 10−2 1.64
227308_x_at LTBP3 latent transforming growth factor beta binding protein 3 2.22 × 10−3 1.53
213765_at MFAP5 microfibrillar associated prot 5 3.51 × 10−3 1.61
213764_s_at MFAP5 microfibrillar associated prot 5 3.23 × 10−3 1.53
210605_s_at MFGE8 milk fat globule-EGF factor 8 protein 1.80 × 10−1 1.75
202291_s_at MGP matrix Gla protein 3.10 × 10−4 7.14
207847_s_at MUC1 mucin 1, cell surface associated 1.58 × 10−1 2.38
213693_s_at MUC1 mucin 1, cell surface associated 2.03 × 10−2 2.04
204114_at NID2 nidogen 2 (osteonidogen) 2.32 × 10−3 2.83
223315_at NTN4 netrin 4 1.76 × 10−4 14.27
201860_s_at PLAT plasminogen activator, tissue 2.56 × 10−2 2.15
211668_s_at PLAU plasminogen activator, urokinase 2.43 × 10−1 1.99
228224_at PRELP proline/arginine-rich end leucine-rich repeat protein 2.74 × 10−2 3.46
204223_at PRELP proline/arginine-rich end leucine-rich repeat protein 3.27 × 10−2 3.27
205923_at RELN reelin 3.58 × 10−8 9.15
202376_at SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 6.25 × 10−2 2.05
204614_at SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 9.41 × 10−2 5.27
209723_at SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 5.41 × 10−3 2.25
200986_at SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 2.27 × 10−1 1.72
205352_at SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.54 × 10−3 2.71
213493_at SNED1 sushi, nidogen and EGF-like domains 1 3.24 × 10−2 2.47
213488_at SNED1 sushi, nidogen and EGF-like domains 1 2.30 × 10−1 1.94
205236_x_at SOD3 superoxide dismutase 3, extracellular 1.15 × 10−1 1.71
202363_at SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 5.31 × 10−3 2.13
201858_s_at SRGN serglycin 3.34 × 10−4 8.11
201859_at SRGN serglycin 3.81 × 10−4 4.87
219552_at SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 1.07 × 10−1 1.70
213247_at SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 6.04 × 10−2 1.70
226506_at THSD4 thrombospondin, type I, domain containing 4 6.68 × 10−4 3.97
222835_at THSD4 thrombospondin, type I, domain containing 4 5.26 × 10−5 3.43
219058_x_at TINAGL1 tubulointerstitial nephritis antigen-like 1 8.12 × 10−3 2.50
216333_x_at TNXA
TNXB
tenascin XA pseudogene tenascin XB 7.97 × 10−5 11.18
206093_x_at TNXA
TNXB
tenascin XA pseudogene tenascin XB 5.32 × 10−5 10.76
213451_x_at TNXA
TNXB
tenascin XA pseudogene tenascin XB 1.65 × 10−4 9.71
208609_s_at TNXB tenascin XB 7.07 × 10−5 8.99
Focal Adhesion Points
Probe Set ID Gene Symbol Gene Title adj-pval FC Probe Set ID Gene Symbol Gene Title adj-pval FC
205730_s_at ABLIM3 actin binding LIM protein family, member 3 1.06 × 10−1 1.53 200965_s_at ABLIM1 actin binding LIM protein 1 2.02 × 10−5 4.17
213497_at ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 6.59 × 10−2 1.61 205882_x_at ADD3 adducin 3 (gamma) 6.45 × 10−3 1.59
205268_s_at ADD2 adducin 2 (beta) 8.16 × 10−4 7.50 201752_s_at ADD3 adducin 3 (gamma) 9.71 × 10−3 1.56
205771_s_at AKAP7 A kinase (PRKA) anchor prot 7 1.03 × 10−1 1.58 227529_s_at AKAP12 A kinase (PRKA) anchor prot 12 6.81 × 10−3 8.03
205257_s_at AMPH amphiphysin 1.45 × 10−7 6.02 227530_at AKAP12 A kinase (PRKA) anchor prot 12 4.43 × 10−3 6.10
1552619_a_at ANLN anillin, actin binding protein 3.48 × 10−2 2.47 210517_s_at AKAP12 A kinase (PRKA) anchor prot 12 6.53 × 10−3 4.66
222608_s_at ANLN anillin, actin binding protein 4.60 × 10−2 2.25 202920_at ANK2 ankyrin 2, neuronal 8.40 × 10−3 2.34
203526_s_at APC adenomatous polyposis coli 3.34 × 10−3 1.60 206385_s_at ANK3 ankyrin 3, node of Ranvier (ankyrin G) 3.69 × 10−3 3.16
204492_at ARHGAP11A Rho GTPase activating protein 11A 3.11 × 10−2 2.12 227337_at ANKRD37 ankyrin repeat domain 37 4.35 × 10−6 6.04
37577_at ARHGAP19 Rho GTPase activating protein 19 9.72 × 10−4 1.72 204671_s_at ANKRD6 ankyrin repeat domain 6 3.20 × 10−2 2.12
206298_at ARHGAP22 Rho GTPase activating protein 22 8.57 × 10−3 1.58 204672_s_at ANKRD6 ankyrin repeat domain 6 5.69 × 10−2 1.96
201288_at ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.85 × 10−2 1.54 228368_at ARHGAP20 Rho GTPase activating prot 20 1.15 × 10−4 5.72
204092_s_at AURKA aurora kinase A 2.07 × 10−2 2.88 227911_at ARHGAP28 Rho GTPase activating prot 28 1.07 × 10−3 2.38
208079_s_at AURKA aurora kinase A 3.80 × 10−2 2.45 206167_s_at ARHGAP6 Rho GTPase activating prot 6 1.09 × 10−1 1.65
209464_at AURKB aurora kinase B 1.04 × 10−2 2.92 205109_s_at ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 1.49 × 10−1 1.53
205294_at BAIAP2 BAI1-associated protein 2 2.67 × 10−3 1.51 201615_x_at CALD1 caldesmon 1 1.61 × 10−1 1.79
210334_x_at BIRC5 baculoviral IAP repeat-containing 5 1.01 × 10−2 2.69 201616_s_at CALD1 caldesmon 1 1.89 × 10−2 1.53
202094_at BIRC5 baculoviral IAP repeat-containing 5 4.10 × 10−2 2.63 236473_at CC2D2A coiled-coil and C2 domain containing 2A 2.18 × 10−3 2.56
202095_s_at BIRC5 baculoviral IAP repeat-containing 5 1.72 × 10−2 2.47 203139_at DAPK1 death-associated protein kinase 1 2.66 × 10−2 3.97
220935_s_at CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.91 × 10−7 1.78 229800_at DCLK1 Doublecortin-like kinase 1 1.78 × 10−1 1.99
204962_s_at CENPA centromere protein A 3.83 × 10−2 2.88 217208_s_at DLG1 discs, large homolog 1 (Drosophila) 6.19 × 10−3 2.32
210821_x_at CENPA centromere protein A 4.21 × 10−3 1.98 202515_at DLG1 discs, large homolog 1 (Drosophila) 1.59 × 10−3 1.72
205046_at CENPE centromere protein E, 312 kDa 7.08 × 10−2 2.65 202514_at DLG1 discs, large homolog 1 (Drosophila) 6.69 × 10−3 1.72
209172_s_at CENPF centromere protein F, 350/400 ka (mitosin) 1.33 × 10−2 2.98 230229_at DLG1 Discs, large homolog 1 (Drosophila) 1.49 × 10−1 1.63
207828_s_at CENPF centromere protein F, 350/400 ka (mitosin) 2.29 × 10−2 2.94 202516_s_at DLG1 discs, large homolog 1 (Drosophila) 5.92 × 10−2 1.60
231772_x_at CENPH centromere protein H 2.74 × 10−2 1.82 203881_s_at DMD dystrophin 1.06 × 10−4 5.02
214804_at CENPI centromere protein I 5.29 × 10−2 1.96 208086_s_at DMD dystrophin 2.36 × 10−2 1.58
207590_s_at CENPI centromere protein I 1.62 × 10−2 1.88 227081_at DNALI1 dynein, axonemal, light intermediate chain 1 2.64 × 10−2 1.64
223513_at CENPJ centromere protein J 2.83 × 10−2 1.69 226875_at DOCK11 dedicator of cytokinesis 11 4.24 × 10−4 1.78
222848_at CENPK centromere protein K 1.00 × 10−1 1.94 1554863_s_at DOK5 docking protein 5 1.93 × 10−2 1.59
1554271_a_at CENPL centromere protein L 1.69 × 10−1 1.54 214844_s_at DOK5 docking protein 5 2.98 × 10−3 1.52
218741_at CENPM centromere protein M 1.86 × 10−2 2.36 220161_s_at EPB41L4B erythrocyte membrane protein band 4.1 like 4B 5.64 × 10−2 2.33
219555_s_at CENPN centromere protein N 9.25 × 10−3 1.89 209829_at FAM65B family with sequence similarity 65, member B 3.97 × 10−2 2.58
222118_at CENPN centromere protein N 1.24 × 10−1 1.84 206707_x_at FAM65B family with sequence similarity 65, member B 3.02 × 10−2 2.20
228559_at CENPN centromere protein N 8.63 × 10−2 1.74 226129_at FAM83H family with sequence similarity 83, member H 2.04 × 10−2 1.75
226118_at CENPO centromere protein O 6.22 × 10−2 1.78 227948_at FGD4 FYVE, RhoGEF and PH domain containing 4 9.89 × 10−4 3.94
219294_at CENPQ centromere protein Q 5.50 × 10−2 1.56 230559_x_at FGD4 FYVE, RhoGEF and PH domain containing 4 3.65 × 10−3 2.66
205642_at CEP110 centrosomal protein 110 kDa 6.59 × 10−3 1.87 225167_at FRMD4A FERM domain containing 4A 1.45 × 10−2 2.04
239413_at CEP152 centrosomal protein 152 kDa 3.34 × 10−3 1.71 225163_at FRMD4A FERM domain containing 4A 8.39 × 10−3 1.98
218542_at CEP55 centrosomal protein 55 kDa 2.63 × 10−2 2.44 225168_at FRMD4A FERM domain containing 4A 2.22 × 10−2 1.76
206324_s_at DAPK2 death-associated protein kinase 2 7.47 × 10−2 1.73 1560031_at FRMD4A FERM domain containing 4A 1.07 × 10−3 1.71
227666_at DCLK2 doublecortin-like kinase 2 7.38 × 10−2 1.52 208476_s_at FRMD4A FERM domain containing 4A 7.85 × 10−3 1.69
207147_at DLX2 distal-less homeobox 2 1.94 × 10−2 6.12 1554034_a_at FRMD4A FERM domain containing 4A 2.32 × 10−1 1.57
215116_s_at DNM1 dynamin 1 2.03 × 10−4 3.83 239290_at FRMPD4 FERM and PDZ domain containing 4 1.74 × 10−1 1.56
219279_at DOCK10 dedicator of cytokinesis 10 2.60 × 10−2 1.66 203037_s_at MTSS1 metastasis suppressor 1 2.31 × 10−3 4.32
213160_at DOCK2 dedicator of cytokinesis 2 1.12 × 10−4 1.76 212096_s_at MTUS1 mitochondrial tumor supp 1 1.02 × 10−1 2.47
205003_at DOCK4 dedicator of cytokinesis 4 1.44 × 10−1 1.54 212095_s_at MTUS1 mitochondrial tumor supp 1 1.08 × 10−1 1.74
206710_s_at EPB41L3 erythrocyte membrane protein band 4.1-like 3 1.31 × 10−2 3.52 228098_s_at MYLIP myosin regulatory light chain interacting protein 5.16 × 10−2 1.57
212681_at EPB41L3 erythrocyte membrane protein band 4.1-like 3 1.38 × 10−2 3.22 220319_s_at MYLIP myosin regulatory light chain interacting protein 4.55 × 10−2 1.50
211776_s_at EPB41L3 erythrocyte membrane protein band 4.1-like 3 1.48 × 10−2 3.20 237206_at MYOCD myocardin 8.62 × 10−3 3.85
218980_at FHOD3 formin homology 2 domain containing 3 7.93 × 10−3 3.13 213782_s_at MYOZ2 myozenin 2 8.68 × 10−2 2.16
238621_at FMN1 formin 1 6.44 × 10−3 2.47 207148_x_at MYOZ2 myozenin 2 8.91 × 10−2 2.07
1555471_a_at FMN2 formin 2 2.05 × 10−2 1.85 219073_s_at OSBPL10 oxysterol binding protein-like 10 3.31 × 10−2 2.11
223618_at FMN2 formin 2 2.05 × 10−2 1.82 209621_s_at PDLIM3 PDZ and LIM domain 3 8.38 × 10−2 3.31
215017_s_at FNBP1L formin binding protein 1-like 3.68 × 10−3 1.52 213684_s_at PDLIM5 PDZ and LIM domain 5 6.28 × 10−3 1.87
230645_at FRMD3 FERM domain containing 3 2.69 × 10−1 1.63 221994_at PDLIM5 PDZ and LIM domain 5 2.46 × 10−3 1.81
230831_at FRMD5 FERM domain containing 5 1.02 × 10−2 2.87 203242_s_at PDLIM5 PDZ and LIM domain 5 1.86 × 10−3 1.68
238756_at GAS2L3 Growth arrest-specific 2 like 3 1.22 × 10−2 2.33 216804_s_at PDLIM5 PDZ and LIM domain 5 4.90 × 10−3 1.60
235709_at GAS2L3 growth arrest-specific 2 like 3 2.92 × 10−2 1.81 207717_s_at PKP2 plakophilin 2 2.96 × 10−2 3.09
226308_at HAUS8 HAUS augmin-like complex, subunit 8 3.75 × 10−2 1.71 201927_s_at PKP4 plakophilin 4 2.90 × 10−1 1.68
226364_at HIP1 Huntingtin interacting protein 1 1.05 × 10−3 2.73 227148_at PLEKHH2 pleckstrin homology domain containing, family H member 2 3.16 × 10−3 3.05
205425_at HIP1 huntingtin interacting protein 1 9.54 × 10−3 2.66 203407_at PPL periplakin 7.99 × 10−3 3.20
218934_s_at HSPB7 heat shock 27 kDa protein family, member 7 (cardiovascular) 7.51 × 10−2 2.16 226627_at SEPT8 septin 8 1.20 × 10−1 1.74
227750_at KALRN kalirin, RhoGEF kinase 8.61 × 10−3 1.53 226438_at SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59 kDa, basic component 1) 1.03 × 10−2 1.84
229125_at KANK4 KN motif and ankyrin repeat domains 4 1.76 × 10−2 3.51 214708_at SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59 kDa, basic component 1) 3.83 × 10−2 1.53
204444_at KIF11 kinesin family member 11 4.00 × 10−2 2.43 227179_at STAU2 staufen, RNA binding protein, homolog 2 (Drosophila) 1.58 × 10−2 1.89
236641_at KIF14 kinesin family member 14 1.15 × 10−2 3.50 212565_at STK38L serine/threonine kinase 38 like 5.74 × 10−5 1.94
206364_at KIF14 kinesin family member 14 5.29 × 10−2 2.87 212572_at STK38L serine/threonine kinase 38 like 5.09 × 10−3 1.53
219306_at KIF15 kinesin family member 15 1.87 × 10−2 2.65 202796_at SYNPO synaptopodin 7.05 × 10−2 2.18
221258_s_at KIF18A kinesin family member 18A 1.25 × 10−2 2.79 227662_at SYNPO2 synaptopodin 2 1.29 × 10−1 3.30
222039_at KIF18B kinesin family member 18B 6.34 × 10−2 2.25 213135_at TIAM1 T-cell lymphoma invasion and metastasis 1 1.12 × 10−1 1.65
218755_at KIF20A kinesin family member 20A 1.17 × 10−2 2.81 209904_at TNNC1 troponin C type 1 (slow) 6.34 × 10−2 2.76
205235_s_at KIF20B kinesin family member 20B 1.83 × 10−2 1.95 215389_s_at TNNT2 troponin T type 2 (cardiac) 5.06 × 10−2 3.22
216969_s_at KIF22 kinesin family member 22 9.75 × 10−2 1.92 210276_s_at TRIOBP TRIO and F-actin binding prot 6.96 × 10−2 1.52
202183_s_at KIF22 kinesin family member 22 6.19 × 10−3 1.65 223279_s_at UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 6.84 × 10−3 1.79
204709_s_at KIF23 kinesin family member 23 3.68 × 10−2 2.55 238868_at UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 1.37 × 10−1 1.66
244427_at KIF23 Kinesin family member 23 2.68 × 10−3 1.76
209408_at KIF2C kinesin family member 2C 3.86 × 10−2 2.95
211519_s_at KIF2C kinesin family member 2C 2.04 × 10−2 2.80
218355_at KIF4A kinesin family member 4A 3.29 × 10−2 2.60
209680_s_at KIFC1 kinesin family member C1 1.72 × 10−2 2.43
206316_s_at KNTC1 kinetochore associated 1 1.88 × 10−2 1.86
224823_at MYLK myosin light chain kinase 1.91 × 10−1 1.72
236718_at MYO10 myosin X 1.05 × 10−3 1.86
244350_at MYO10 myosin X 1.45 × 10−2 1.70
241966_at MYO5A myosin VA (heavy chain 12, myoxin) 2.21 × 10−2 1.51
201774_s_at NCAPD2 non-SMC condensin I complex, subunit D2 1.30 × 10−1 1.57
212789_at NCAPD3 non-SMC condensin II complex, subunit D3 5.55 × 10−2 1.56
218663_at NCAPG non-SMC condensin I complex, subunit G 1.03 × 10−1 2.23
218662_s_at NCAPG non-SMC condensin I complex, subunit G 8.24 × 10−2 2.11
219588_s_at NCAPG2 non-SMC condensin II complex, subunit G2 2.03 × 10−2 1.86
212949_at NCAPH non-SMC condensin I complex, subunit H 3.01 × 10−2 2.58
204641_at NEK2 NIMA (never in mitosis gene a)-related kinase 2 2.34 × 10−2 2.97
211080_s_at NEK2 NIMA (never in mitosis gene a)-related kinase 2 4.89 × 10−3 2.64
223381_at NUF2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) 8.44 × 10−2 2.67
219978_s_at NUSAP1 nucleolar and spindle associated protein 1 1.39 × 10−1 2.48
218039_at NUSAP1 nucleolar and spindle associated protein 1 2.98 × 10−2 2.42
204972_at OAS2 2’-5’-oligoadenylate synthetase 2, 69/71 kDa 2.83 × 10−1 1.68
209626_s_at OSBPL3 oxysterol binding protein-like 3 5.77 × 10−2 1.67
238575_at OSBPL6 oxysterol binding protein-like 6 1.17 × 10−2 2.13
223805_at OSBPL6 oxysterol binding protein-like 6 9.15 × 10−3 2.09
218644_at PLEK2 pleckstrin 2 4.94 × 10−3 2.63
218009_s_at PRC1 protein regulator of cytokinesis 1 2.03 × 10−2 2.37
222077_s_at RACGAP1 Rac GTPase activating protein 1 1.49 × 10−2 1.99
219263_at RNF128 ring finger protein 128 2.50 × 10−2 3.03
230730_at SGCD sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) 2.17 × 10−2 3.65
213543_at SGCD sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) 2.12 × 10−2 3.57
228602_at SGCD sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) 6.41 × 10−2 3.55
214492_at SGCD sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) 5.41 × 10−3 3.18
210329_s_at SGCD sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) 8.64 × 10−3 2.72
210330_at SGCD sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) 3.47 × 10−2 2.43
207302_at SGCG sarcoglycan, gamma (35 kDa dystrophin-associated glycoprotein) 1.42 × 101 3.09
217678_at SLC7A11 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 7.43 × 10−2 1.53
209921_at SLC7A11 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 3.18 × 10−2 1.53
1556583_a_at SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.96 × 10−1 1.85
241752_at SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 2.94 × 10−1 1.61
200783_s_at STMN1 stathmin 1 1.16 × 10−2 2.14
222557_at STMN3 stathmin-like 3 1.48 × 10−2 1.83
212703_at TLN2 talin 2 5.18 × 10−4 1.84
206117_at TPM1 tropomyosin 1 (alpha) 5.66 × 10−3 2.26
210052_s_at TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis) 1.78 × 10−2 2.56
1555938_x_at VIM vimentin 2.81 × 10−2 2.00
202663_at WIPF1 WAS/WASL interacting protein family, member 1 6.39 × 10−3 1.64
202664_at WIPF1 WAS/WASL interacting protein family, member 1 5.61 × 10−4 1.58
202665_s_at WIPF1 WAS/WASL interacting protein family, member 1 2.97 × 10−3 1.51
Cytoskeleton
Probe Set ID Gene Symbol Gene Title adj-pval FC Probe Set ID Gene Symbol Gene Title adj-pval FC
205132_at ACTC1 actin, alpha, cardiac muscle 1 1.80 × 10−3 4.22 203563_at AFAP1 actin filament associated protein 1 2.27 × 10−3 1.90
230925_at APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.66 × 10−2 2.50 206488_s_at CD36 CD36 molecule (thrombospondin receptor) 1.46 × 10−8 20.69
226292_at CAPN5 calpain 5 2.20 × 10−4 1.51 209555_s_at CD36 CD36 molecule (thrombospondin receptor) 3.58 × 10−8 19.05
217523_at CD44 CD44 molecule (Indian blood group) 1.89 × 10−2 1.64 228766_at CD36 CD36 molecule (thrombospondin receptor) 2.97 × 10−6 11.94
220115_s_at CDH10 cadherin 10, type 2 (T2-cadherin) 1.94 × 10−1 1.90 201005_at CD9 CD9 molecule 7.82 × 10−4 2.58
207030_s_at CSRP2 cysteine and glycine-rich protein 2 1.93 × 10−2 1.74 201131_s_at CDH1 cadherin 1, type 1, E-cadherin (epithelial) 4.31 × 10−2 2.54
211126_s_at CSRP2 cysteine and glycine-rich protein 2 2.34 × 10−2 1.71 204726_at CDH13 cadherin 13, H-cadherin (heart) 3.20 × 10−2 2.60
214724_at DIXDC1 DIX domain containing 1 1.14 × 10−2 1.53 203256_at CDH3 cadherin 3, type 1, P-cadherin (placental) 3.21 × 10−2 1.84
202668_at EFNB2 ephrin-B2 1.85 × 10−1 3.24 200621_at CSRP1 cysteine and glycine-rich protein 1 1.70 × 10−2 1.56
205031_at EFNB3 ephrin-B3 2.95 × 10−10 2.47 203716_s_at DPP4 dipeptidyl-peptidase 4 4.05 × 10−2 1.93
1555480_a_at FBLIM1 filamin binding LIM protein 1 1.07 × 10−2 1.89 211478_s_at DPP4 dipeptidyl-peptidase 4 2.67 × 10−1 1.80
1554795_a_at FBLIM1 filamin binding LIM protein 1 2.26 × 10−2 1.61 203717_at DPP4 dipeptidyl-peptidase 4 1.08 × 10−1 1.67
225258_at FBLIM1 filamin binding LIM protein 1 2.87 × 10−3 1.56 227955_s_at EFNA5 ephrin-A5 4.68 × 10−2 1.94
204379_s_at FGFR3 fibroblast growth factor receptor 3 9.77 × 10−2 2.01 214036_at EFNA5 ephrin-A5 1.32 × 10−1 1.53
242592_at GPR137C G protein-coupled receptor 137C 1.50 × 10−2 2.18 201983_s_at EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) 1.75 × 10−3 1.82
235961_at GPR161 G protein-coupled receptor 161 4.34 × 10−4 1.56 201809_s_at ENG endoglin 2.31 × 10−3 2.06
230369_at GPR161 G protein-coupled receptor 161 3.44 × 10−2 1.53 201539_s_at FHL1 four and a half LIM domains 1 8.39 × 10−3 6.09
229055_at GPR68 G protein-coupled receptor 68 7.83 × 10−3 1.70 214505_s_at FHL1 four and a half LIM domains 1 6.48 × 10−3 5.76
234303_s_at GPR85 G protein-coupled receptor 85 7.25 × 10−2 2.04 210299_s_at FHL1 four and a half LIM domains 1 1.55 × 10−3 5.39
203632_s_at GPRC5B G protein-coupled receptor, family C, group 5, member B 1.76 × 10−1 1.92 210298_x_at FHL1 four and a half LIM domains 1 6.70 × 10−3 5.18
222899_at ITGA11 integrin, alpha 11 1.21 × 10−2 1.59 201540_at FHL1 four and a half LIM domains 1 4.21 × 10−4 3.20
227314_at ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 5.68 × 10−2 2.53 222853_at FLRT3 fibronectin leucine rich transmembrane protein 3 7.40 × 10−4 3.36
205032_at ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 3.78 × 10−2 2.41 219250_s_at FLRT3 fibronectin leucine rich transmembrane protein 3 4.52 × 10−2 2.12
228080_at LAYN layilin 4.84 × 10−3 2.59 212950_at GPR116 G protein-coupled receptor 116 1.98 × 10−1 3.52
216250_s_at LPXN leupaxin 2.03 × 10−5 3.08 213094_at GPR126 G protein-coupled receptor 126 9.65 × 10−4 5.14
210869_s_at MCAM melanoma cell adhesion molecule 1.03 × 10−6 7.67 232267_at GPR133 G protein-coupled receptor 133 1.46 × 10−2 2.44
209087_x_at MCAM melanoma cell adhesion molecule 1.08 × 10−6 7.38 228949_at GPR177 G protein-coupled receptor 177 3.16 × 10−4 2.71
211340_s_at MCAM melanoma cell adhesion molecule 1.07 × 10−6 6.81 228950_s_at GPR177 G protein-coupled receptor 177 3.49 × 10−3 2.63
209086_x_at MCAM melanoma cell adhesion molecule 2.85 × 10−8 5.09 221958_s_at GPR177 G protein-coupled receptor 177 1.52 × 10−3 2.50
203062_s_at MDC1 mediator of DNA damage checkpoint 1 3.87 × 10−3 1.58 229105_at GPR39 G protein-coupled receptor 39 2.66 × 10−2 1.90
212843_at NCAM1 neural cell adhesion molecule 1 8.99 × 10−7 4.58 212070_at GPR56 G protein-coupled receptor 56 2.12 × 10−2 1.78
227394_at NCAM1 neural cell adhesion molecule 1 1.26 × 10−6 3.16 203108_at GPRC5A G protein-coupled receptor, family C, group 5, member A 2.08 × 10−3 8.54
213438_at NFASC neurofascin homolog (chicken) 3.12 × 10−2 2.57 202638_s_at ICAM1 intercellular adhesion molecule 1 1.31 × 10−1 2.21
230242_at NFASC neurofascin homolog (chicken) 5.17 × 10−3 2.19 202637_s_at ICAM1 intercellular adhesion molecule 1 7.04 × 10−2 1.70
243645_at NFASC neurofascin homolog (chicken) 2.12 × 10−3 2.03 205885_s_at ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2.52 × 10−1 1.71
219773_at NOX4 NADPH oxidase 4 8.60 × 10−2 1.80 216331_at ITGA7 integrin, alpha 7 1.01 × 10−2 3.76
37966_at PARVB parvin, beta 4.78 × 10−10 2.88 209663_s_at ITGA7 integrin, alpha 7 4.49 × 10−2 3.70
204629_at PARVB parvin, beta 2.58 × 10−8 2.28 204990_s_at ITGB4 integrin, beta 4 8.14 × 10−2 1.67
37965_at PARVB parvin, beta 7.26 × 10−5 1.98 226189_at ITGB8 integrin, beta 8 2.19 × 10−2 1.69
216253_s_at PARVB parvin, beta 4.90 × 10−3 1.80 220765_s_at LIMS2 LIM and senescent cell antigen-like domains 2 1.80 × 10−2 1.80
225977_at PCDH18 protocadherin 18 4.98 × 10−3 2.18 226974_at NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 4.84 × 10−2 2.02
225975_at PCDH18 protocadherin 18 1.29 × 10−2 1.76 212448_at NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 9.48 × 10−2 1.78
207011_s_at PTK7 PTK7 protein tyrosine kinase 7 3.74 × 10−3 2.23 212445_s_at NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 1.04 × 10−1 1.76
1555324_at PTK7 PTK7 protein tyrosine kinase 7 5.32 × 10−3 1.78 202150_s_at NEDD9 neural precursor cell expressed, developmentally down-regulated 9 3.21 × 10−3 1.97
207419_s_at RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.39 × 10−2 2.37 202149_at NEDD9 neural precursor cell expressed, developmentally down-regulated 9 3.93 × 10−4 1.90
213603_s_at RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 8.95 × 10−3 2.13 228635_at PCDH10 protocadherin 10 2.55 × 10−3 3.91
223168_at RHOU ras homolog gene family, member U 1.13 × 10−5 3.13 223435_s_at PCDHA1 PCDHA10 PCDHA11
PCDHA12 PCDHA13 PCDHA2 PCDHA3 PCDHA4 PCDHA5 PCDHA6 PCDHA7 PCDHA8 PCDHA9 PCDHAC1 PCDHAC2
protocadherin alpha 1 protocadherin alpha 10 protocadherin alpha 11 protocadherin alpha 12 protocadherin alpha 13 protocadherin alpha 2 protocadherin alpha 3 protocadherin alpha 4 protocadherin alpha 5 protocadherin alpha 6 protocadherin alpha 7 protocadherin alpha 8 protocadherin alpha 9 protocadherin alpha C, 1
protocadherin alpha C, 2
2.40 × 10−3 2.23
201286_at SDC1 syndecan 1 7.78 × 10−3 3.11 202565_s_at SVIL supervillin 5.25 × 10−3 3.45
201287_s_at SDC1 syndecan 1 3.47 × 10−3 3.04 202566_s_at SVIL supervillin 5.31 × 10−2 2.32
202898_at SDC3 syndecan 3 2.98 × 10−2 1.66 206702_at TEK TEK tyrosine kinase, endothelial 4.91 × 10−4 3.67
218087_s_at SORBS1 sorbin and SH3 domain containing 1 1.05 × 10−2 4.48
222513_s_at SORBS1 sorbin and SH3 domain containing 1 3.04 × 10−2 2.95
208850_s_at THY1 Thy-1 cell surface antigen 2.80 × 10−1 1.91
213869_x_at THY1 Thy-1 cell surface antigen 1.38 × 10−1 1.77
208851_s_at THY1 Thy-1 cell surface antigen 2.50 × 10−1 1.70
217853_at TNS3 tensin 3 5.51 × 10−5 2.61
217979_at TSPAN13 tetraspanin 13 1.08 × 10−4 4.67
227307_at TSPAN18 Tetraspanin 18 2.78 × 10−4 3.95
227236_at TSPAN2 tetraspanin 2 1.85 × 10−1 2.19
214606_at TSPAN2 tetraspanin 2 1.19 × 10−1 1.83
LINC Complexes
Probe Set ID Gene Symbol Gene Title adj-pval FC Probe Set ID Gene Symbol Gene Title adj-pval FC
203145_at SPAG5 sperm associated antigen 5 2.63 × 10−2 2.48 219888_at SPAG4 sperm associated antigen 4 8.03 × 10−2 1.87
Nucleoskeleton
Probe Set ID Gene Symbol Gene Title adj-pval FC Probe Set ID Gene Symbol Gene Title adj-pval FC
205436_s_at H2AFX H2A histone family, member X 1.88 × 10−2 1.71 215071_s_at HIST1H2AC histone cluster 1, H2ac 2.13 × 10−2 1.70
214463_x_at HIST1H4J histone cluster 1, H4j 1.24 × 10−2 1.53 214455_at HIST1H2BC histone cluster 1, H2bc 1.34 × 10−2 1.71
201795_at LBR lamin B receptor 8.68 × 10−4 1.88 236193_at HIST1H2BC histone cluster 1, H2bc 1.57 × 10−2 1.60
203276_at LMNB1 lamin B1 8.33 × 10−2 2.42 209911_x_at HIST1H2BD histone cluster 1, H2bd 1.63 × 10−2 1.63
209753_s_at TMPO thymopoietin 5.06 × 10−3 1.98 208527_x_at HIST1H2BE histone cluster 1, H2be 4.22 × 10−3 1.54
224944_at TMPO thymopoietin 5.13 × 10−3 1.84 232035_at HIST1H4B Histone cluster 1, H4b 5.60 × 10−3 1.96
209754_s_at TMPO thymopoietin 2.51 × 10−2 1.83 208180_s_at HIST1H4B Histone cluster 1, H4b 1.34 × 10−1 1.59
203432_at TMPO thymopoietin 1.02 × 10−1 1.64
Secreted Factors
Probe Set ID Gene Symbol Gene Title adj-pval FC Probe Set ID Gene Symbol Gene Title adj-pval FC
205608_s_at ANGPT1 angiopoietin 1 1.27 × 10−4 3.04 231773_at ANGPTL1 angiopoietin-like 1 3.01 × 10−2 2.12
205609_at ANGPT1 angiopoietin 1 7.38 × 10−6 2.97 224339_s_at ANGPTL1 angiopoietin-like 1 7.59 × 10−2 1.71
213001_at ANGPTL2 angiopoietin-like 2 1.03 × 10−1 1.50 239183_at ANGPTL1 angiopoietin-like 1 8.51 × 10−2 1.50
220988_s_at C1QTNF3 C1q and tumor necrosis factor related protein 3 9.99 × 10−2 1.78 221009_s_at ANGPTL4 angiopoietin-like 4 6.59 × 10−3 2.88
1405_i_at CCL5 chemokine (C-C motif) ligand 5 1.12 × 10−1 1.56 223333_s_at ANGPTL4 angiopoietin-like 4 1.80 × 10−1 2.11
203666_at CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) 6.11 × 10−3 2.98 209546_s_at APOL1 apolipoprotein L, 1 1.42 × 10−1 1.78
209687_at CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) 1.99 × 10−2 2.24 221087_s_at APOL3 apolipoprotein L, 3 6.19 × 10−2 1.83
222484_s_at CXCL14 chemokine (C-X-C motif) ligand 14 5.41 × 10−4 7.47 205239_at AREG amphiregulin 1.14 × 10−1 1.75
218002_s_at CXCL14 chemokine (C-X-C motif) ligand 14 1.22 × 10−3 6.46 202701_at BMP1 bone morphogenetic protein 1 5.22 × 10−2 1.54
204602_at DKK1 dickkopf homolog 1 (Xenopus laevis) 2.42 × 10−2 2.04 205289_at BMP2 bone morphogenetic protein 2 2.65 × 10−2 2.54
219908_at DKK2 dickkopf homolog 2 (Xenopus laevis) 7.38 × 10−4 4.54 205290_s_at BMP2 bone morphogenetic protein 2 8.44 × 10−2 2.25
228952_at ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 5.77 × 10−7 4.95 211518_s_at BMP4 bone morphogenetic protein 4 1.68 × 10−2 4.03
229088_at ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 5.38 × 10−7 4.83 206176_at BMP6 bone morphogenetic protein 6 2.52 × 10−2 2.33
205066_s_at ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 3.10 × 10−5 4.76 239349_at C1QTNF7 C1q and tumor necrosis factor related protein 7 2.49 × 10−1 1.53
205065_at ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 3.78 × 10−7 3.82 202357_s_at C2
CFB
complement component 2 complement factor B 3.16 × 10−3 3.85
205110_s_at FGF13 fibroblast growth factor 13 3.58 × 10−8 4.73 217767_at C3 complement component 3 2.71 × 10−1 2.42
214240_at GAL galanin prepropeptide 9.61 × 10−2 1.59 208451_s_at C4A
C4B
complement component 4A (Rodgers blood group) complement component 4B (Chido blood group) 1.98 × 10−1 1.83
205505_at GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) 1.70 × 10−5 1.66 206407_s_at CCL13 chemokine (C-C motif) ligand 13 8.28 × 10−2 3.52
240509_s_at GREM2 gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) 2.66 × 10−3 3.23 216598_s_at CCL2 chemokine (C-C motif) ligand 2 5.57 × 10−4 8.18
235504_at GREM2 gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) 9.10 × 10−3 3.11 206508_at CD70 CD70 molecule 1.14 × 10−1 2.44
220794_at GREM2 gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) 2.06 × 10−2 2.76 213800_at CFH complement factor H 8.63 × 10−5 6.48
206326_at GRP gastrin-releasing peptide 3.05 × 10−2 1.59 215388_s_at CFH
CFHR1
complement factor H complement factor H-related 1 4.95 × 10−6 10.91
203821_at HBEGF heparin-binding EGF-like growth factor 1.31 × 10−1 1.64 206910_x_at CFHR2 complement factor H-related 2 8.81 × 10−3 1.60
203819_s_at IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 4.18 × 10−2 2.51 209395_at CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.10 × 10−2 4.08
203820_s_at IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 6.30 × 10−2 2.13 209396_s_at CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 4.55 × 10−2 1.94
212143_s_at IGFBP3 insulin-like growth factor binding protein 3 1.26 × 10−2 1.54 206315_at CRLF1 cytokine receptor-like factor 1 8.40 × 10−3 3.23
227760_at IGFBPL1 insulin-like growth factor binding protein-like 1 3.76 × 10−3 1.94 209774_x_at CXCL2 chemokine (C-X-C motif) ligand 2 1.37 × 10−1 3.03
204773_at IL11RA interleukin 11 receptor, alpha 1.36 × 10−3 1.97 207850_at CXCL3 chemokine (C-X-C motif) ligand 3 2.50 × 10−1 2.07
206172_at IL13RA2 interleukin 13 receptor, alpha 2 8.39 × 10−2 3.56 219837_s_at CYTL1 cytokine-like 1 1.99 × 10−1 2.02
227997_at IL17RD interleukin 17 receptor D 9.70 × 10−2 1.70 219501_at ENOX1 ecto-NOX disulfide-thiol exchanger 1 1.82 × 10−2 2.35
222062_at IL27RA interleukin 27 receptor, alpha 4.50 × 10−4 3.73 226213_at ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.84 × 10−2 2.49
205926_at IL27RA interleukin 27 receptor, alpha 5.58 × 10−4 1.67 205738_s_at FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) 2.56 × 10−1 1.70
226218_at IL7R interleukin 7 receptor 9.41 × 10−2 1.71 203980_at FABP4 fatty acid binding protein 4, adipocyte 5.11 × 10−2 2.16
205798_at IL7R interleukin 7 receptor 1.78 × 10−1 1.59 205117_at FGF1 fibroblast growth factor 1 (acidic) 8.61 × 10−3 2.95
231798_at NOG noggin 6.76 × 10−5 3.98 1552721_a_at FGF1 fibroblast growth factor 1 (acidic) 1.47 × 10−2 2.71
206343_s_at NRG1 neuregulin 1 6.34 × 10−3 2.68 208240_s_at FGF1 fibroblast growth factor 1 (acidic) 9.05 × 10−2 1.73
206237_s_at NRG1 neuregulin 1 7.90 × 10−2 2.15 231382_at FGF18 Fibroblast growth factor 18 1.71 × 10−1 2.09
208230_s_at NRG1 neuregulin 1 1.20 × 10−2 1.90 211029_x_at FGF18 fibroblast growth factor 18 2.54 × 10−1 1.64
204766_s_at NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 2.22 × 10−5 1.59 221577_x_at GDF15 growth differentiation factor 15 3.41 × 10−2 2.03
213131_at OLFM1 olfactomedin 1 1.82 × 10−1 1.71 206614_at GDF5 growth differentiation factor 5 4.96 × 10−2 2.01
213125_at OLFML2B olfactomedin-like 2B 2.17 × 10−1 1.93 201348_at GPX3 glutathione peroxidase 3 (plasma) 2.15 × 10−2 3.24
218162_at OLFML3 olfactomedin-like 3 3.28 × 10−2 1.72 214091_s_at GPX3 glutathione peroxidase 3 (plasma) 7.64 × 10−2 1.99
222719_s_at PDGFC platelet derived growth factor C 2.01 × 10−3 1.61 209960_at HGF hepatocyte growth factor (hepapoietin A; scatter factor) 7.99 × 10−2 3.24
201578_at PODXL podocalyxin-like 1.11 × 10−2 5.15 210997_at HGF hepatocyte growth factor (hepapoietin A; scatter factor) 2.26 × 10−2 2.96
210195_s_at PSG1 pregnancy specific beta-1-glycoprotein 1 2.14 × 10−1 1.82 210998_s_at HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3.94 × 10−2 1.80
208134_x_at PSG2 pregnancy specific beta-1-glycoprotein 2 1.56 × 10−3 3.17 210619_s_at HYAL1 hyaluronoglucosaminidase 1 1.86 × 10−3 3.19
203399_x_at PSG3 pregnancy specific beta-1-glycoprotein 3 8.06 × 10−3 3.33 209540_at IGF1 insulin-like growth factor 1 (somatomedin C) 2.78 × 10−1 1.97
215821_x_at PSG3 pregnancy specific beta-1-glycoprotein 3 2.08 × 10−2 2.47 209542_x_at IGF1 insulin-like growth factor 1 (somatomedin C) 2.03 × 10−1 1.57
211741_x_at PSG3 pregnancy specific beta-1-glycoprotein 3 1.76 × 10−2 2.22 202718_at IGFBP2 insulin-like growth factor binding protein 2, 36 kDa 8.69 × 10−2 3.80
204830_x_at PSG5 pregnancy specific beta-1-glycoprotein 5 8.14 × 10−3 3.53 201508_at IGFBP4 insulin-like growth factor binding protein 4 1.12 × 10−1 1.68
209738_x_at PSG6 pregnancy specific beta-1-glycoprotein 6 7.00 × 10−3 3.35 203426_s_at IGFBP5 insulin-like growth factor binding protein 5 2.55 × 10−2 3.31
208106_x_at PSG6 pregnancy specific beta-1-glycoprotein 6 4.99 × 10−3 3.26 211958_at IGFBP5 insulin-like growth factor binding protein 5 2.16 × 10−1 2.76
209594_x_at PSG9 pregnancy specific beta-1-glycoprotein 9 5.91 × 10−3 3.49 1555997_s_at IGFBP5 insulin-like growth factor binding protein 5 1.64 × 10−1 2.46
207733_x_at PSG9 pregnancy specific beta-1-glycoprotein 9 1.20 × 10−2 3.03 203425_s_at IGFBP5 insulin-like growth factor binding protein 5 1.58 × 10−1 1.80
212187_x_at PTGDS prostaglandin D2 synthase 21 kDa (brain) 5.94 × 10−3 1.91 206295_at IL18 interleukin 18 (interferon-gamma-inducing factor) 3.70 × 10−2 3.75
211748_x_at PTGDS prostaglandin D2 synthase 21 kDa (brain) 2.12 × 10−3 1.69 207526_s_at IL1RL1 interleukin 1 receptor-like 1 1.32 × 10−1 2.07
206631_at PTGER2 prostaglandin E receptor 2 (subtype EP2), 53 kDa 4.68 × 10−2 1.71 242809_at IL1RL1 Interleukin 1 receptor-like 1 2.38 × 10−1 1.60
211737_x_at PTN pleiotrophin 7.25 × 10−2 3.28 221111_at IL26 interleukin 26 4.68 × 10−2 3.44
209465_x_at PTN pleiotrophin 4.83 × 10−2 3.24 209821_at IL33 interleukin 33 1.79 × 10−1 1.50
209466_x_at PTN pleiotrophin 1.03 × 10−1 2.42 205207_at IL6 interleukin 6 (interferon, beta 2) 2.42 × 10−4 3.20
209897_s_at SLIT2 slit homolog 2 (Drosophila) 1.55 × 10−2 1.98 204863_s_at IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 1.97 × 10−2 1.99
205016_at TGFA transforming growth factor, alpha 4.19 × 10−2 3.27 211000_s_at IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 1.21 × 10−2 1.88
203085_s_at TGFB1 transforming growth factor, beta 1 7.50 × 103 1.60 204926_at INHBA inhibin, beta A 1.44 × 10−2 2.47
236561_at TGFBR1 Transforming growth factor, beta receptor 1 4.05 × 10−2 1.71 210511_s_at INHBA inhibin, beta A 4.64 × 10−3 2.42
203887_s_at THBD thrombomodulin 2.94 × 10−1 2.27 205266_at LIF leukemia inhibitory factor (cholinergic differentiation factor) 7.91 × 10−2 2.44
239336_at THBS1 Thrombospondin 1 1.84 × 10−1 1.58 219181_at LIPG lipase, endothelial 3.51 × 10−2 2.89
227420_at TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1 3.38 × 10−3 1.71 205381_at LRRC17 leucine rich repeat containing 17 2.67 × 10−4 18.57
219478_at WFDC1 WAP four-disulfide core domain 1 3.17 × 10−2 5.38 216320_x_at MST1 macrophage stimulating 1 (hepatocyte growth factor-like) 1.05 × 10−1 1.53
221029_s_at WNT5B wingless-type MMTV integration site family, member 5B 5.20 × 10−4 2.39 231361_at NLGN1 Neuroligin 1 4.86 × 10−2 3.33
223537_s_at WNT5B wingless-type MMTV integration site family, member 5B 2.99 × 10−2 1.65 205893_at NLGN1 neuroligin 1 7.72 × 10−2 3.23
204501_at NOV nephroblastoma overexpressed gene 2.01 × 10−2 2.95
214321_at NOV nephroblastoma overexpressed gene 1.69 × 10−2 2.60
217525_at OLFML1 olfactomedin-like 1 5.70 × 10−2 3.66
213075_at OLFML2A olfactomedin-like 2A 1.64 × 10−2 2.12
205729_at OSMR oncostatin M receptor 6.53 × 10−2 1.71
224942_at PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.20 × 10−2 1.88
1559400_s_at PAPPA pregnancy-associated plasma protein A, pappalysin 1 3.28 × 10−2 1.84
201981_at PAPPA pregnancy-associated plasma protein A, pappalysin 1 3.78 × 10−2 1.74
224940_s_at PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.72 × 10−2 1.73
224941_at PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.36 × 10−2 1.69
228128_x_at PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.13 × 10−2 1.64
205560_at PCSK5 proprotein convertase subtilisin/kexin type 5 2.21 × 10−3 2.70
213652_at PCSK5 Proprotein convertase subtilisin/kexin type 5 5.18 × 10−4 2.66
205559_s_at PCSK5 proprotein convertase subtilisin/kexin type 5 1.23 × 10−3 2.52
227759_at PCSK9 proprotein convertase subtilisin/kexin type 9 2.34 × 10−2 1.97
216867_s_at PDGFA platelet-derived growth factor alpha polypeptide 2.46 × 10−2 1.97
222860_s_at PDGFD platelet derived growth factor D 1.50 × 10−1 1.57
1555778_a_at POSTN periostin, osteoblast specific factor 4.41 × 10−3 4.30
214981_at POSTN periostin, osteoblast specific factor 2.20 × 10−3 2.96
210809_s_at POSTN periostin, osteoblast specific factor 8.30 × 10−3 2.47
207808_s_at PROS1 protein S (alpha) 3.88 × 10−3 1.51
213421_x_at PRSS3 protease, serine, 3 2.41 × 10−2 2.68
210367_s_at PTGES prostaglandin E synthase 3.17 × 10−4 4.21
207388_s_at PTGES prostaglandin E synthase 4.23 × 10−2 2.51
224950_at PTGFRN prostaglandin F2 receptor negative regulator 4.86 × 10−2 1.78
211892_s_at PTGIS prostaglandin I2 (prostacyclin) synthase 4.91 × 10−2 2.06
210702_s_at PTGIS prostaglandin I2 (prostacyclin) synthase 1.13 × 10−1 1.70
208131_s_at PTGIS prostaglandin I2 (prostacyclin) synthase 2.43 × 10−2 1.67
211756_at PTHLH parathyroid hormone-like hormone 6.78 × 10−2 3.45
206300_s_at PTHLH parathyroid hormone-like hormone 7.08 × 10−2 2.86
210355_at PTHLH parathyroid hormone-like hormone 1.70 × 10−1 2.21
206157_at PTX3 pentraxin-related gene, rapidly induced by IL-1 beta 1.47 × 10−4 2.21
201482_at QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.19 × 10−3 1.68
223824_at RNLS renalase, FAD-dependent amine oxidase 5.18 × 10−4 1.74
204035_at SCG2 secretogranin II (chromogranin C) 2.66 × 10−2 2.56
205475_at SCRG1 scrapie responsive protein 1 6.88 × 10−7 7.73
213716_s_at SECTM1 secreted and transmembrane 1 3.32 × 10−2 3.29
203071_at SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 6.35 × 10−2 2.54
203788_s_at SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 6.34 × 10−4 2.51
203789_s_at SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 3.13 × 10−3 1.64
33323_r_at SFN stratifin 1.80 × 10−1 2.42
223122_s_at SFRP2 secreted frizzled-related prot 2 2.86 × 10−1 2.33
204051_s_at SFRP4 secreted frizzled-related prot 4 4.79 × 10−2 4.23
204052_s_at SFRP4 secreted frizzled-related prot 4 1.56 × 10−1 2.58
210665_at TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 4.02 × 10−2 3.69
210664_s_at TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.35 × 10−2 3.50
209676_at TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.96 × 10−2 3.35
213258_at TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.61 × 10−2 3.24
228121_at TGFB2 transforming growth factor, beta 2 1.08 × 10−6 5.13
209909_s_at TGFB2 transforming growth factor, beta 2 5.47 × 10−5 3.64
204731_at TGFBR3 transforming growth factor, beta receptor III 2.06 × 10−1 1.70
203083_at THBS2 thrombospondin 2 4.84 × 10−6 2.83
202644_s_at TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.61 × 10−3 3.88
202643_s_at TNFAIP3 tumor necrosis factor, alpha-induced protein 3 4.35 × 10−3 3.52
206025_s_at TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.57 × 10−2 2.29
206026_s_at TNFAIP6 tumor necrosis factor, alpha-induced protein 6 3.57 × 10−2 2.15
210260_s_at TNFAIP8 tumor necrosis factor, alpha-induced protein 8 5.99 × 10−4 2.01
208296_x_at TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.11 × 10−3 1.94
235737_at TSLP thymic stromal lymphopoietin 1.72 × 10−1 2.02
210513_s_at VEGFA vascular endothelial growth factor A 9.18 × 10−2 1.57
205648_at WNT2 wingless-type MMTV integration site family member 2 2.83 × 10−1 2.08
202643_s_at TNFAIP3 tumor necrosis factor, alpha-induced protein 3 4.35 × 10−3 3.52
206025_s_at TNFAIP6 tumor necrosis factor, alpha-induced protein 6 1.57 × 10−2 2.29
206026_s_at TNFAIP6 tumor necrosis factor, alpha-induced protein 6 3.57 × 10−2 2.15
210260_s_at TNFAIP8 tumor necrosis factor, alpha-induced protein 8 5.99 × 10−4 2.01
208296_x_at TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.11 × 10−3 1.94
235737_at TSLP thymic stromal lymphopoietin 1.72 × 10−1 2.02
210513_s_at VEGFA vascular endothelial growth factor A 9.18 × 10−2 1.57
205648_at WNT2 wingless-type MMTV integration site family member 2 2.83 × 10−1 2.08