Figure 6.

A fragment of fold space: (a) The model folds generated from the secondary structure sequence for a small protein is shown with each structure represented as a dot in a projected space (as in Figure 2). The known family from which the SSE sequence was taken is coloured red, and the model structures that correspond to other known folds are coloured green. The size of the coloured spheres is proportional to the number of family members. (b) The greater number of novel folds (white) has been likened to the preponderance of dark matter in the Universe.