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Combined application of prexasertib and adavosertib enhances CDK1 activation. (a,b) Quantification (top) and representative western blot images (bottom) for indicated phospho- and total proteins in HNSCC cell lines, after 6 (a) or 72 h (b) of treatment with indicated drugs. All graphs: *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001, ****, p ≤ 0.0001 relative to vehicle controls.
