Table 1.
Disease | BC RNAs | Description |
---|---|---|
Alzheimer’s Disease | Up-regulation | Overexpressed in Brodmann’s area 9 and accumulated in the soma |
Fragile X Syndrome | Down-regulation | BC1-KO mice are similar to FMRP-KO mice |
Fragile X Premutation Disorders | Mislocalization | CGG repeats inhibits dendritic localization of BC RNAs |
Systemic Lupus Erythematosus | Mislocalization | Anti-BC antibodies inhibit dendritic localization of BC RNAs |