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Biosynthetic pathways of long-chain (≥ C20) polyunsaturated fatty acids (LC-PUFAs) of ω3 and ω6 families from dietary essential α-linolenic (ALA, 18:3n-3) and linoleic (LA, 18:2n-6) acids, respectively, by elongation and desaturation reactions. Adapted from (Carmona-Antoñanzas et al., 2011; Monroig et al., 2011; Sprecher, 2000; Voss et al., 1991); modified after (Trattner, 2009; Vestergeren, 2014; Yan, 2016).
