Table 4.
The comparison of Collagen Ӏ protein expression in co-silencing multiple AKAPs with or without cyclic adenosine monophosphate (cAMP) donors.
| Treatment | Collagen Ӏ | |||||
|---|---|---|---|---|---|---|
| Control | siControl | siMultiple | ||||
| −TGF-β1 | +TGF-β1 | −TGF-β1 | +TGF-β1 | −TGF-β1 | +TGF-β1 | |
| Control | 0.18 ± 0.04 | 1.00 ± 0.00 | ||||
| Fenoterol 10 μM | 0.23 ± 0.07 | 0.71 ± 0.06 | ||||
| Rolipram 10 μM | 0.11 ± 0.03 | 0.68 ± 0.09 | ||||
| Cilostamide 10 μM | 0.11 ± 0.03 | 0.59 ± 0.10 | ||||
| 0.08 ± 0.03 | 1.00 ± 0.00 | 0.04 ± 0.01 | 0.25 ± 0.06 | |||
| Control | 0.16 ± 0.09 | 1.00 ± 0.00 | 0.09 ± 0.02 | 0.54 ± 0.09 | ||
| Fenoterol 10 μM | 0.08 ± 0.02 | 0.75 ± 0.08 | 0.07 ± 0.03 | 0.25 ± 0.08 | ||
| Control | 0.02 ± 0.06 | 1.00 ± 0.00 | 0.04 ± 0.02 | 0.59 ± 0.08 | ||
| Rolipram 10 μM | 0.08 ± 0.05 | 0.76 ± 0.05 | 0.05 ± 0.01 | 0.75 ± 0.22 | ||
| Control | 0.04 ± 0.01 | 1.00 ± 0.00 | 0.05 ± 0.02 | 0.55 ± 0.13 | ||
| Cilostamide 10 μM | 0.03 ± 0.01 | 0.86 ± 0.29 | 0.02 ± 0.01 | 0.72 ± 0.23 | ||